Aventis Cropscience S.a.

Rhone-poulenc Agro

Bayer Cropscience S.a.

Scynexis Chemistry & Automation, Inc.

Susan Marie McComb

Yves Ribeill

Scot Kevin Huber

Michael James Malaska

David Teh-Wei Chou

Adalberto Perez De Leon

Joachim Dickhaut

Harald Jakobi

David T Chou

Waltraud Hempel

Adalberto A Perez De Leon

Stephen David Lindell

Daniela Jans

Jutta Maria Waibel

Jörg Tiebes

Maria-Theresia Thönessen

Jaleh Abedi

Vincent Lee Salgado

Reed Nathan Royalty

Henry David Smith, Iii

Pierre Monnet

Susan Mary Cramp

Maria Asuncion Canales

The present invention relates to the use of substituted aryl- and heteroarylpropargylamines of the formula (I) where

Substituted propargylamines

A method of controlling parasites in or on an animal comprising orally administering to the animal a parasiticidally effective, substantially non-emetic 1-arylpyrazole.

Control of arthropods in animals

Devices and processes for synthesizing, purifying and analyzing large numbers of compounds for use in combinatorial libraries, are disclosed. The processes involve generating a series of compounds in multi-well plates or multi-tube racks, purifying the reaction mixtures, analyzing the purified compounds, and optionally performing bioassays on the compounds. The information regarding the compounds is stored in a central database. The devices include one or more multi-tube arrays, a purification device, means for transferring the contents of the tubes, a solvent evaporator, analytical instrumentation, and, optionally, a weighing instrument. The multi-tube array(s) optionally include a cover, which can be placed on or removed from the array by computer control. By correlating the orientation of tubes from one stage to the next, it is possible to use a single bar code or other identifying mark for each multi-tube array rather than for each individual tube. This simplifies data collection for large numbers of compounds.

Method and apparatus for synthesizing characterizing and assaying combinatorial libraries

A method of controlling parasites in or on an animal comprising orally administering to the animal a parasitically effective, substantially non-emetic 1-arylpyrazole.

Growing community of inventors

Bad Soden, Germany

Susan Marie McComb