Sterling Drug Inc.

Sterling Winthrop Inc.

Sanofi

Susan J Ward

Malcolm R Bell

Virendra Kumar

Thomas E D'Ambra

Edward R Bacon

John P Mallamo

Philip M Carabateas

Michael A Eissenstat

Edward Richard Bacon

2-R.sub.2 --R.sub.4 -substituted-3-R.sub.3 --CO-1-�(C-attached-N-heteryl)-(Alk) .sub.n !-1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.

3-arylcarbonyl-1-(C-attached-N-heteryl)-1H-indoles

2--R.sub.2 --R.sub.4 -substituted-3--R.sub.3 --CO--1--[(C-attached-N-heteryl)-(Alk).sub.n ]--1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.

3-arylcarbonyl-1(C-attached-N-heteryl)-1H-indoles

2-R.sub.2 -R.sub.4 -substitutea-3-R.sub.3 -CO-1-[(C-attached-N-heteryl)(Alk).sub.n ]-1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.

Compounds of the formula ##STR1## wherein Alk is lower-alkylene;

Morpholinoalkylindenes as antiglaucoma agents

Antiglaucoma compositions containing 2- and 3-aminomethyl-6-arylcarbonyl- or 6-phenylthio-2,3-dihydropyrrolo-[1,2,3-de]-1,4-benzoxazines as the active component thereof and the method of use thereof in the treatment of glaucoma.

Anti-glaucoma compositions containing 2- and

Antiglaucoma compositions containing 3-R.sub.3 -4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles and a method of use thereof in the treatment of glaucoma.

Antiglaucoma compositions containing

2-R.sub.2 -R.sub.4 -substituted-3-R.sub.3 -CO-1-[(C-attached-N-herteryl)-(Alk).sub.n ]-1H-indoles useful as analgesic, anti-rheumatic, anti-inflammatory or anti-glaucoma agents.

Antiglaucoma compositions containing 3-aryl-carbonyl-1-aminoalkyl-1H-indoles, as the active component thereof, and a method of use thereof in the treatment of glaucoma.

Growing community of inventors

East Greenbush, NY, United States of America

Susan J Ward