E.i. Dupont De Nemours and Company

Shell Internationale Research Maatschappij, B.v.

Susan J Turner

Michael T Clark

Thomas W Naisby

William W Wood

Andrew C Gray

Michael Pearson

Tarnia M Machin

Compounds of the general formula ##STR1## where R.sup.2 and R.sup.3 together, or R.sup.3 and R.sup.4 together, represent an optionally substituted hydrocarbyloxy chain; the ring is optionally substituted at any or each of the remaining sites R.sup.5, R.sup.6 and R.sup.2 or R.sup.4 : n represents 0 or 1; and X represents a cyano group, a group --COOH or a salt, ester or amido derivative thereof; are biocidal, showing activity against fungi, yeast, bacteria and nematodes. Some such compounds, and intermediates therefore, are novel.

Bicyclic or tricyclic biocidal compounds

The invention provides a method of combating a microorganism which comprises allowing a heterocyclic pentalene derivative of general formula I ##STR1## wherein X represents an oxygen atom, a sulphur atom or an --SO-- moiety; Y represents a sulphur, selenium or tellurium atom, provided that when Y represents a selenium or tellurium atom X is an oxygen atom; and R.sup.1 and R.sup.2 together represent a --CH.sub.2 --C(CH.sub.3).sub.2 --CCl(CONH.sub.2)-- or --CH.sub.2 --A--CH.sub.2 -- linkage where A is a --CH.sub.2 --, --CH(CH.sub.3)-- or --S(O).sub.n -- moiety, where n is 0, 1 or 2; provided that when X is an oxygen atom and Y is a sulphur atom R.sup.1 and R.sup.2 together represent a --CH.sub.2 --S(O).sub.n --CH.sub.2 -- linkage and when X is an --SO-- moiety and A is a S(O).sub.n --, n is 2; to act on the microorganism or its environment; and such derivatives for use as a therapeutic substance.

Heterocyclic pentalene derivatives for use in combating microorganisms

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Sittingbourne, United Kingdom

Susan J Turner