Viacyte, Inc.

Cythera, Inc.

Susan Eliazer

Kevin Allen D'Amour

Emmanuel Edward Baetge

Alan D Agulnick

Evert Kroon

Kevin Allen D'amour

Kevin D' Amour

Disclosed herein are cell cultures comprising PDX1-positive endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified PDX1-positive endoderm cells as well as methods for enriching, isolating and purifying PDX1-positive endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of endoderm cells, such as PDX1-positive foregut endoderm cells and PDX1-negative definitive endoderm cells, are also disclosed.

PDX1 positive foregut endoderm cells and methods of production

This disclosure relates to compositions comprising human preprimitive streak cells and/or human mesendoderm cells as well as methods for their production. Additionally, disclosed herein are methods of identifying factors useful in the further differentiation of preprimitive streak and mesendoderm cell types.

Methods of making human primitive ectoderm cells

Disclosed herein are cell cultures comprising dorsal and/or ventral PDX1-positive foregut endoderm cells and methods of producing the same. Also disclosed herein are cell populations comprising substantially purified dorsal and/or ventral PDX1-positive foregut endoderm cells as well as methods for enriching, isolating and purifying dorsal and/or ventral PDX1-positive foregut endoderm cells from other cell types. Methods of identifying differentiation factors capable of promoting the differentiation of dorsal and/or ventral PDX1-positive foregut endoderm cells, are also disclosed.

Methods of producing human foregut endoderm cells expressing PDX1 from human definitive endoderm

Anterior endoderm cells and methods of production

PDX1-expressing dorsal and ventral foregut endoderm

Methods for making anterior foregut endoderm

PDX1 expressing endoderm

Disclosed herein are methods of identifying one or more differentiation factors that are useful for differentiating cells in a cell population comprising definitive endoderm cells into cells which are capable of forming tissues and/or organs that are derived from the gut tube.

Methods for identifying factors for differentiating definitive endoderm

Growing community of inventors

San Diego, CA, United States of America

Susan Eliazer