Neuro-bio Ltd

Susan Adele Greenfield

Sara Garcia-Rates

Christopher Pepper

Paul Morrill

Chris Pepper

Jesus Seco Moral

Roger Prades Cosano

Henry Tu

Chris Fegan

Gwenael Pottiez

Sara Esther Garcia-Rates

Sergio Rotondo

A cyclic polypeptide, derivative or analogue thereof, comprising an amino acid sequence derived from the C-terminus of acetylcholinesterase (AChE), or a truncation thereof.

Neurodegenerative disorders

The invention relates to neurodegenerative disorders, and in particular to novel peptides, peptidomimetics, compositions, therapies and methods for treating such conditions, for example Alzheimer's disease.

Modified peptides for use in treating neurodegenerative disorders

The invention relates to cancer, and in particular to novel pharmaceutical compositions, therapies and methods for treating, preventing or ameliorating cancer, and especially metastatic disease. The invention also relates to diagnostic and prognostic methods for cancer and metastatic disease, and biomarkers for these conditions.

Cancer

A cyclic polypeptide, derivative or analogue thereof, comprising an amino acid sequence derived from the C-terminus of acetylcholinesterase (ACh E), or a truncation thereof.

The invention relates to cyclic polypeptides derived from the C-terminus of acetylcholinesterase for use in treating or preventing cancer or metastatic disease.

Cyclic acetylcholinesterase C-terminal peptide in the treatment or prevention of cancer or metastasis

The invention relates to antibodies, and in particular, to antibodies used in the diagnosis and treatment of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. The invention extends to methods of diagnosis and therapy of neurodegenerative disorders, and to assays and screens for isolating novel therapeutic compounds for treating such diseases.

Antibody that recognises the T14 peptide of AChE

The invention relates to novel peptides, compositions, therapies and methods for treating neurodegenerative disorders, for example Alzheimer's disease.

Cyclic acetylcholinesterase c-terminal peptide in the treatment or prevention of cancer or metastasis

A cyclic polypeptide, derivative or analog thereof, comprising an amino acid sequence derived from the C-terminus of acetylcholinesterase (ACh E), or a truncation thereof.

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Abingdon, United Kingdom

Susan Adele Greenfield