Sterix Limited

Surinder Kuman Chander

Michael John Reed

Barry Victor Lloyd Potter

Atul Purohit

Matthew Paul Leese

Fabrice Jourdan

Simon Paul Newman

The present invention provides a compound comprising a steroidal ring system and an optional group Rselected from any one of &#x2014;OH, a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group; wherein the D ring of the steroidal ring system is substituted by a group Rof the formula -L-R, wherein L is an optional linker group and Ris selected from groups which are or which comprise one of a nitrite group, an alcohol, an ester, an ether, an amine and an alkene, provided that when Ris or comprises an alcohol, L is present; and wherein the A ring of the steroidal ring system is substituted at position 2 or 4 with a group R, wherein Ris a hydrocarbyl group.

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Slough, United Kingdom

Surinder Kuman Chander