Verily Life Sciences LLC

Suresh Alla

John D Perreault

Seung Ah Lee

Tamara Troy

Chinmay Belthangady

Faisal Mahmood Kashif

Victor Marcel Acosta

Methods and systems disclosed herein may be operable to detect a presence or absence of an analyte in human tissue. An example method includes operating one or more light sources to illuminate a plurality of optodes with excitation light. Each optode is embedded in tissue at a respective location. The excitation light causes the optodes to emit emission light and the optodes are sensitive to at least one analyte such that the emission light emitted by the optodes is indicative of a presence or absence of at least one analyte in the tissue. An optical filter arrangement includes for each optode in the plurality of optodes a corresponding set of one or more optical filters. The method includes obtaining detector information from a detector arrangement optically coupled to the optical filter arrangement, and detecting the at least one analyte based on the detector information.

Systems and methods for optode imaging

A device and a method to measure the concentrations of oxygenated and deoxygenated hemoglobin in tissue around a tumor via near-infrared (NIR) spectroscopy with a photonic mixer device (PMD) is described.

Continuous monitoring of tumor hypoxia using near-infrared spectroscopy and tomography with a photonic mixer device

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San Jose, CA, United States of America

Suresh Alla