Pierce Biotechnology, Inc.

Dyomics Gmbh

Life Technologies Corporation

Surbhi Desai

Matthias S Wenzel

Peter T Czerney

Frank G Lehmann

Boguslawa Dworecki

Greg Hermanson

Marie Christine Nlend

Brian Webb

Bernd G Schweder

Gregory John Kilmer

Peter Alan Bell

Kyle R Gee

Aleksey Rukavishnikov

Shih-Jung Huang

Suk Hong

Wilhelm G Frank

Robert Aggeler

Brian David Wolf

Scott Sweeney

Matthew Baker

Steven Jerome Moore

Craig E Smith

Eric Leigh Hommema

Ramesh Ganapathy

Zakir S Murtaza

Hongfang Wang

John David Dwenger

Stefan Reiley Freeman

Priya Rangaraj

Stephen D Shiflett

Michael Stanaitis

Mark Rickerd

Kari Severson

Ineabel Horneij

Boguslawa R Dworecki

Brian Lynn Webb

This disclosure relates to the field of fluorescent dyes, and in particular, compositions and methods for increasing fluorescent signals and the reduction of fluorescent quenching.

Compositions and methods for enhanced fluorescence

Compounds used as labels with properties comparable to known fluorescent compounds. The compounds can be conjugated to proteins and nucleic acids for biological imaging and analysis. Synthesis of the compounds, formation and use of the conjugated compounds, and specific non-limiting examples of each are provided.

Fluorescent compounds

Compounds useful as labels with properties comparable to known fluorescent compounds. The compounds are conjugated to proteins and nucleic acids for biological imaging and analysis. Synthesis of the compounds, formation and use of the conjugated compounds, and specific non-limiting examples of each are provided.

Benzocyanine compounds

The disclosure provides compositions, kits and methods comprising an absorbent pad comprising a fibrous material and a liquid formulation comprising a luminescent substrate for identifying and quantifying biomolecule analytes.

Chemiluminescent and fluorescent substrate pads and uses thereof

Cyanine compounds

Staining compositions and methods for use with a matrix, such as an electrophoretic gel, containing separated biopolymers. The compositions including an acid, an organic solvent, and a generally planar, fluid-permeable gel contact sheet consisting primarily of a non-cellulosic material. The acid and organic solvent may be sorbed to the fluid-permeable gel contact sheet, or may be sorbed to a layers contactable with a non-gel contact side of the gel contact sheet. In one embodiment, the composition is a source electrophoretic stain composition including a staining reagent. In one embodiment, the composition is a sink electrophoretic stain composition including a sorbent.

Kit for use in electrophoretic matrix staining

Compounds used as labels with properties comparable to known fluorescent compounds. The compounds are conjugated to proteins and nucleic acids for biological imaging and analysis. Synthesis of the compounds, formation and use of the conjugated compounds, and specific non-limiting examples of each are provided.

Benzopyrylium compounds

An electroblotting system including a cassette configured to receive a membrane and a material impregnated with at least one of proteins or nucleic acids. The cassette is connectable to a base such that a current is passable through the cassette to cause at least some of the proteins or nucleic acids to be transferred from the impregnated material to the membrane. The cassette has a first portion, a second portion configured to be releasably coupled to the first portion, and a coupling mechanism configured to releasably couple the first portion to the second portion. The cassette further includes an actuator operatively coupled to the coupling mechanism such that manual depression of the actuator causes the coupling mechanism to release the first portion relative to the second portion.

Electroblotting device

Growing community of inventors

Rockford, IL, United States of America

Surbhi Desai