Lawrence Livermore National Security, LLC

Supin Chen

Kedar G Shah

Satinderpall Singh Pannu

Susant K Patra

Jason Jones

Angela C Tooker

Vanessa M Tolosa

Sarah H Felix

Anna Nikolaevna Ivanovskaya

Kye Young Lee

Marissa Crosetti

Timir B Datta-Chaudhuri

The present disclosure relates to a modular system for deep brain stimulation (DBS) and electrocorticography (ECoG). The system may have an implantable neuromodulator for generating electrical stimulation signals adapted to be applied to a desired region of a brain via an attached electrode array. An aggregator module may be used for collecting and aggregating electrical signals and transmitting the electrical signals to the neuromodulator. A control module may be used which is in communication with the aggregator module for controlling generation of the electrical signals and transmitting the electrical signals to the aggregator.

Implantable neuromodulation system for closed-loop stimulation and recording simultaneously at multiple brain sets

A cylindrical microelectrode array having an elongated cylindrical core, and a multilayer structure conformally folded around and affixed to the cylindrical core so as to extend between opposite ends of the core. The multilayer structure has integrated sections including an electrode section with electrodes exposed through electrically insulating layers, a connector section with conductive bond pads for interfacing with external electronics, and a cable section with conductive traces encapsulated in electrically insulating layers and which connect between the electrodes and their corresponding bond pads. The array may be fabricated using a planar multilayer structure having the electrode, connector, and cable sections, and conformally folding the multilayer structure around and affixing to the cylindrical core. The cable section in particular may be conformally coiled around and affixed to the cylindrical core so that the electrical conduits helically extend between the connector and electrode sections.

Cylindrical microelectrode array for neural stimulation and recording

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Palos Verdes, CA, United States of America

Supin Chen