Antigenics, Inc.

Sunil Mehta

Paul Slusarewicz

Jessica Baker Flechtner

Sofija Andjelic

Brian H Barber

Kenya Prince-Cohane

Hybrid antigens comprising an antigenic domain and improved heat shock protein binding domains are described which are useful for the induction of an immune response to the antigenic domain and thus can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.

Heat shock protein-based vaccines and immunotherapies

Hybrid antigens comprising at least one antigenic domain, at least one heat shock protein binding domain, and at least one improved peptide linker there between are described which are useful for the induction of an immune response to the antigenic domain when administered alone or in a complex with at least one heat shock protein. The hybrid antigens and complexes can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.

Growing community of inventors

Durham, NC, United States of America

Sunil Mehta