Bristol-myers Squibb Compnay

Syngene International Limited

Sunil Kumar Mandal

James Aaron Balog

Steven P Seitz

David K Williams

Audris Huang

Jay A Markwalder

William R Ewing

Ashvinikumar V Gavai

Wayne D Vaccaro

Philip Michael Sher

John S Tokarski

John E Starrett, Jr

Derek J Norris

Wen-Ching Han

Chongqing Sun

Francis Lee

Yeheng Zhu

Laxman Pasunoori

George V Delucca

Andrew P Degnan

Yanting Huang

Mikkel V Debenedetto

Amy C Hart

Daniel O'Malley

Patrice Gill

Haiquan Fang

Claude A Quesnelle

Libing Chen

Shefali Srivastava

Matthew D Hill

Maheswaran Sivasamban Karatholuvhu

Scott A Bolton

William D Schmitz

Jennifer Inghrim

Hong Huang

Alexander Gm Klausener

Mikkel V DeBenedetto

Vikas Kumar

Lalit Kumar Jena

Gagan Kukreja

Rohit Saxena

Vishwanath Gade

Jeevan Singh Verma

Kiran K C

Ravikumar Suryanarayana Saragur

Daniel O'malley

Francis Y Lee

John E Starrett

Jr John E Starrett

Jennifer Donnell

The present invention discloses a fused heterocyclic compound of formula (I), wherein, R, Y, Q, A, G, m and E are as defined in the detailed description. The present invention further discloses methods for their preparation and use of the compounds of formula (I) as a pest control agent.

Fused heterocyclic compounds and their use as pest control agents

There are disclosed compounds of formula (I) that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention. 

IDO inhibitors

There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or autoimmune diseases utilizing the compounds of the invention.

The present invention is directed to tricyclic compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

Tricyclic compounds as anticancer agents

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are agonists, partial agonists and modulators of the NPY Y4 receptor and may be used for the treatment and prophylaxis of various diseases and conditions.

Diaminocyclohexane compounds and uses thereof

Growing community of inventors

Bengaluru, India

Sunil Kumar Mandal