Abbott Laboratories Corporation

Sunil K Kadam

James B McAlpine

Jill E Hochlowski

Marianna Jackson

James P Karwowski

Patrick E Humphrey

Novel antifungal and antitumor agents having the formula ##STR1## as well as pharmaceutically acceptable salts, esters, amides and pro-drugs thereof, wherein R is selected from the group consisting of ##STR2## Also disclosed are pharmaceutical compositions comprising such compounds, and methods of treatment and processes of manufacture relating thereto.

Dorrigocin antitumor agents

Antifungal dorrigocin derivatives

A compound having the structural formula ##STR1## or a pharmaceutically acceptable salts and prodrugs thereof, wherein R.sup.1 is selected from the group consisting of hydrogen and loweracyl, and R.sup.2 is selected from the group consisting of hydrogen, hydroxyl and methoxyl, as well as methods for the preparation and use thereof.

Multiple drug resistance-attenuating compounds

Growing community of inventors

Kenosha, WI, United States of America

Sunil K Kadam