Il Dong Pharmaceutical Co., Ltd.

Samsung Electronics Co., Ltd.

Sung-Wook Kwon

Sun-Young Park

Kyung-Sun Kim

Dong-Keun Song

Yoon-Suk Lee

Jae-Hoon Kang

Hong-Sub Lee

Ki-jun Kim

Jin-Ah Jeong

Jeong-Guen Kim

Hey-Min Hwang

Ji-Hye Choi

Kyeo-Jin Kim

Jeong-Geun Kim

Jeong-Ah Kim

Ju-Young Jung

An-Na Moon

Jun-Su Ban

Soo-Jin Lee

Sung-Ku Choi

Kyu-Sic Jang

The present disclosure provides autotaxin (ATX) inhibitor compounds and compositions including said compounds. The present disclosure also provides methods of using said compounds and compositions for inhibiting ATX. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.

Autotaxin inhibitor compounds

The present invention provides methods for treating or ameliorating metabolic diseases, cholestatic liver diseases, or organ fibrosis, which comprises administering to a subject a therapeutically effective amount of a pharmaceutical composition comprising an isoxazole derivative, a racemate, an enantiomer, or a diastereoisomer thereof, or a pharmaceutically acceptable salt of the derivative, the racemate, the enantiomer, or the diastereoisomer.

Isoxazole derivatives as nuclear receptor agonists and uses thereof

The present invention relates to isoxazole derivatives, including pharmaceutical compositions and for the preparation of isoxazole derivatives. And more particularly the present invention provided a pharmaceutical composition of isoxazole derivatives for activation of Farnesoid X receptor (FXR, NR1H4).

An air cleaning device is provided. The air cleaning device includes: a main body; a filter configured to be disposed in the main body to purify air; and an image transmitter configured to show a state of the filter to an outside of the main body.

Air cleaning device

Growing community of inventors

Hwaseong-si, South Korea

Sung-Wook Kwon