Pharmabcine Inc.

Lg Chem, Ltd

Korea Atomic Energy Research Institute

Sung-Woo Kim

Jin-San Yoo

Chae-Ok Yun

Young-Guen Kwon

Do-Yun Kim

Too-Hyon Cho

Sam-Sook Sul

Kwi-Hwa Kim

Nahm-Ju Kim

Dong-Heon Lee

Jae-Won Jeon

Young-Woo Park

Geun-Bae Rha

Hyun-Sook Jang

Bo-Jeong Pyun

Mi-Hee Park

Hyeon-Mi Yoo

Sang-Seok Koh

Dong-Sup Lee

Weon-Sup Lee

Sang-Ryeol Shim

Jeong-Eun Kang

John E Namgoong

Jisang Yu

Hyuk Jin Lee

Semi Kim

Weon Sup Lee

Sang Soon Byun

Sang Ryeol Shim

Jae Bong Yoon

Jinsang Yoo

Youngae Lee

Jinhee Choi

Joon-Chul Lee

Min Su Kim

Seon Young Lee

Hey Woong Park

Bo Hyun Kim

Do Yun Kim

Seungjae You

Eun Hee Lee

Ra Young Hwang

Jin San Yoo

Hong Pyo Kim

Nam Ye Kim

Jong Geun Jeong

Ji-Sang Yu

Seon Hwan Oh

Dong-Jin Kim

Miju Park

Do-yun Kim

Hyuk Joon Lee

Kyoung Hee Nahm

Boyoung Jeong

Yun-Soo Lim

Byung-Hak Moon

Sujin Jung

Se-mi Kim

Yeon Ju Kim

Ji Hye Jeong

Joon Chul Lee

Ju Ryoung Nam

Mi Ae Jeon

Hee-Joo Jeon

Se-Hyun Shin

Kwang-Min Park

The present disclosure relates to an antibody specifically binding to epidermal growth factor receptor variant III (EGFRvIII), to nucleic acid coding the antibody, to a vector comprising the nucleic acid, to a host cell, to a preparation method of the antibody, and to a pharmaceutical composition comprising the antibody as an active ingredient for treating a cancer or a tumor.

EGFRvIII antibody and composition comprising same

Provided are an antibody specifically bound to c-Met (c-Met-specific antibody) or fragments thereof, and more specifically, a fully human antibody having high affinity and specificity to c-Met isolated from human Fv(ScFv) phage library, a polynucleotide encoding the antibody, a recombinant vector containing the polynucleotide, a cell transformed with the recombinant vector, and a method of producing the c-Met-specific antibody by culturing the cell, wherein the c-Met-specific antibody may effectively control activity of c-Met in vivo.

Human antibody specific to c-Met and preparation method thereof

The present invention relates to a nickel-based super heat resistant alloy and a method of manufacturing the same. In the nickel-based super heat resistant alloy according to the present invention, an amount of solid solution strengthening elements (chromium, cobalt, molybdenum, or tantalum) is adjusted to improve a mechanical property, such as a creep property, at high temperatures, and aluminum or titanium is included in a predetermined amount to improve a corrosion property. The nickel-based super heat resistant alloy has excellent elongation, strength, and creep properties at normal temperature and high temperatures, and thus it is possible to manufacture parts of, by way of non-limiting example, a thermoelectric power plant, an aircraft, or a very high temperature reactor in various shapes on a large scale.

Nickel-based super heat resistant alloy and method of manufacturing the same

The present invention relates to human monoclonal antibodies neutralizing vascular endothelial growth factor receptor and the use thereof. More specifically, relates to human ScFv molecules neutralizing vascular endothelial growth factor receptor, and a composition for inhibiting angiogenesis and a composition for treating cancer, which contain the human ScFv molecules. The disclosed monoclonal antibody neutralizing vascular endothelial growth factor receptor shows excellent neutralizing ability in living cells, compared to that of a commercially available antibody against vascular endothelial growth factor receptor, and shows the ability to neutralize vascular endothelial growth factor receptor not only in humans, but also in mice and rats. Thus, the monoclonal antibody will be useful in anticancer studies and will be highly effective in cancer treatment.

Human monoclonal antibody neutralizing vascular endothelial growth factor receptor and use thereof

A battery module has a plurality of batteries, each having an electrode assembly mounted in a battery case including a metal layer and a resin layer, as unit cells, are stacked one on another in the thickness direction, wherein the battery module is constructed such that electrode leads of each unit cell are bent and placed on an upper-end sealing part of each unit cell, through-holes for mechanical coupling and electrical connection are formed in the electrode leads and the sealing part such that the through-holes of the electrode leads communicate with the corresponding through-holes of the sealing part, respectively, and conductive coupling members are inserted through the through-holes of the unit cells. The battery module accomplished a maximum reduction in volume, increasing sealability of the sealing part, and easily accomplishing the electrical connection and the mechanical coupling between components.

Battery module of novel structure

Provided is a lithium secondary battery which uses a lithium manganese metal oxide as a cathode active material and a non-graphitic carbon material as an anode active material, and based on the total weight of the electrolyte, contains 0.1 to 20% by weight of a salt represented by Formula I in a lithium salt-containing non-aqueous electrolyte:RXYZ&#x2003;&#x2003;(I) The lithium secondary battery of the present invention can improve low-temperature properties of the battery by increasing the lithium ion-electrode reactivity and decreasing the electrode-interface resistance, via the formation of a charge double layer at the cathode-anode interface upon charging/discharging of the battery at a low temperature, and therefore can be preferably used in medium/large battery systems such as power sources for electric vehicles (EVs) and hybrid electric vehicles (HEVs) requiring operation under severe conditions.

Electrolyte for lithium secondary battery of improved low-temperature property and secondary battery containing the same

The present invention provides a non-aqueous electrolyte-based high power lithium secondary battery having a long-term service life and superior safety at both room temperature and high temperature, even after repeated high-current charging and discharging, wherein the battery comprises a mixture of a particular lithium manganese-metal composite oxide (A) having a spinel structure and a particular lithium nickel-manganese-cobalt composite oxide (B) having a layered structure, as a cathode active material.

Lithium secondary battery with high power

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Daejeon, South Korea

Sung-Woo Kim