Brookhaven Science Associates, Lcc

Sung Won Kim

Jacob Matthew Hooker

Joanna S Fowler

Richard A Ferrieri

David Alexoff

Dohyun Kim

Anat Biegon

A method for providingC-labeled cyanides fromC labeled oxides in a target gas stream retrieved from an irradiated high pressure gaseous target containing O, whereinC labeled oxides are reduced with Hin the presence of a nickel catalyst under a pressure and a temperature sufficient to form a product stream comprising at least about 95%CH, theCHis then combined with an excess of NHin a carrier/reaction stream flowing at an accelerated velocity and the combinedCH4 carrier/reaction stream is then contacted with a platinum (Pt) catalyst particulate supported on a substantially-chemically-nonreactive heat-stable support at a temperature of at least about 900&#xb0; C., whereby a product stream comprising at least about 60% HCN is provided in less than 10 minutes from retrieval of theC labeled oxide.

C-11 cyanide production system

A method for providingC-labeled cyanides fromC labeled oxides in a target gas stream retrieved from an irradiated high pressure gaseous target containing Ois provided, whereinC labeled oxides are reduced with Hin the presence of a nickel catalyst under a pressure and a temperature sufficient to form a product stream comprising at least about 95%CH, theCHis then combined with an excess of NHin a carrier/reaction stream flowing at an accelerated velocity and the combinedCH4 carrier/reaction stream is then contacted with a platinum (Pt) catalyst particulate supported on a substantially-chemically-nonreactive heat-stable support at a temperature of at least about 900 &#xb0; C., whereby a product stream comprising at least about 60%HCN is provided in less than 10 minutes from retrieval of theC labeled oxide.

Radiotracer vorozole compounds for in vivo and in vitro assaying, studying and imaging cytochrome P450 aromatase enzymes in humans, animals, and tissues and methods for making and using the same are provided. [N-radio-methyl] vorozole substantially separated from an N-3 radio-methyl isomer of vorozole is provided. Separation is accomplished through use of chromatography resins providing multiple mechanisms of selectivity.

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Port Jefferson, NY, United States of America

Sung Won Kim