Logone Bio Convergence Research Foundation

Seoul National University

Abion Inc.

Gencurix Inc

Immortality Co., Ltd.

Sung Su Kim

Young Kee Shin

Jun Young Choi

Young Ho Moon

Jin Ju Kim

Sung Youl Hong

Jee Eun Kim

Young Deug Kim, I

Ha Yeon Park

Myung Sun Kim

Heo Bin Yang

Hyun Jeung Choi

Sae Hyung Lee

The present invention relates to a type 1 interferon neutralizing FC-fusion protein and a use thereof and, more specifically, to: a dimer-type polypeptide to which a monomer comprising an interferon receptor fragment or an antibody Fc fragment is bound; a preparation method there for; and a pharmaceutical composition comprising same. The type 1 interferon neutralizing FC-fusion protein of the present invention blocks binding between type 1 interferon and an interferon receptor, and has an excellent ability of inhibiting the signaling and biological activities of interferon, thereby enabling diseases mediated by a type 1 interferon to be effectively treated.

Type 1 interferon neutralizing FC-fusion protein and use thereof

The invention of the present application relates to a use of an antibody binding specifically to ECL-2 of claudin 3 and functional fragments thereof in cancer cell detection, diagnosis, imaging, and application to cancer treatment (anticancer use of the antibody itself, and application to ADC and CAR-expression cells (particularly immune cells)), an antibody that includes a characteristic CDR sequence exerting a remarkable effect in such uses, and a functional fragment thereof.

Antibody binding specifically to ECL-2 of claudin 3, fragment thereof, and use thereof

The present invention relates to a method for determining the DNA quality of a biological sample and, more specifically, to a method for determining the DNA quality of a biological sample by performing a quantitative polymerase chain reaction (PCR) using primers capable of amplifying a target gene, a method for preparing the primers used in the method, and a method for standardizing the amount of detected target gene mutation by using the determined DNA quality. The method of the present invention enables objective evaluation of the DNA quality of a biological sample used in gene analysis and the presentation of objective results on the expression ratio of a gene mutation, thereby providing reliable information in the fields of clinical research and companion diagnosis.

Method for determining nucleic acid quality of biological sample

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Seoul, South Korea

Sung Su Kim