Korea Institute of Science and Technology

Csir

Csir of Scientia

Sung-Kwon Chung

Young-Joo Kim

Jungyeob Ham

Vinesh Jaichand Maharaj

Hak Cheol Kwon

Hyun Ok Yang

Gerda Fouche

Joon Ki Kim

Eric Khorombi

Hyun-Ok Yang

Jin Wook Cha

Rudzani Nthambeleni

Dashnie Naidoo

Jeremiah Senabe

Hak-Cheol Kwon

Myung-soo Kim

Jin-Soo Park

Na-Young Bae

Myung-Sook Oh

A pharmaceutical composition and a food composition including extracts ofsp. for treating dementia, which compositions inhibit the formation of &#x3b2;-amyloid, and a method of preparing the extracts.

Composition for preventing or treating dementia comprising extracts of monsonia species

Composition and method for preventing and/or treating dementia and ameliorating memory impairment and/or improving memory, comprising one or more arylnaphthalene lignan derivatives, namely Justicidin A, 5-methoxyjusticidin A, Chinensinaphthol, and a pharmaceutically-acceptable salt thereof, as active ingredient.

Composition containing arylnaphthalene lignan derivative for preventing and/or treating dementia

Provided are novel use of an extract ofor a compound isolated therefrom for inhibition of &#x3b2;-amyloid production and/or prevention, improvement and/or treatment of a neurodegenerative disease, more specifically a &#x3b2;-amyloid production inhibitor, and/or a composition for prevention or treatment of a neurodegenerative disease containing one or more kinds selected from the group consisting of an extract of, and/or dihydrolycoricidine, 2-methoxypancracine, lycoricidine, and/or lycoricidinol, as an active ingredient; a method for inhibiting &#x3b2;-amyloid production, and/or preventing and/or treating a neurodegenerative disease using the same; and, a method for preparing the same.

[object Object]

This disclosure relates to a composition for prevention or treatment of neurodegenerative disease comprising longan arillus extract, or combined extract comprising longan arillus. The composition exhibits remarkably excellent prevention or treatment effect of neurodegenerative disease by containing longan arillus extract or combined extract comprising longan arillus, and particularly, it may effectively prevent or treat neurodegenerative disease by significantly protecting dopaminergic neurons from neurotoxicity due to MPTP selectively acting on dopaminergic nervous system and neurotoxicity due to aggregation of alpha-synuclein proteins.

Growing community of inventors

Seoul, South Korea

Sung-Kwon Chung