Cj Cheiljedang Corporation

Arkema France

Sung Kwang Son

Yong Uk Shin

Jae Min Lee

Hyo Jin Kim

Ji Hye Lee

Dae Young Kim

So Young Kim

So-Young Kim

Chang Il Seo

Sang Mok Lee

Ji Hyun Lee

Heeseok Lee

Hyun Ah Kim

Kwang Ho Na

Jae Hee Lee

Tae Yeon Kim

Georges Fremy

Jin Sook Chang

Ji-Won Kim

Jun Young Jung

Bina Kim

Eunji Kim

In Kyung Heo

Jee Yeon Bae

Sung Hoo Jhon

Chang Gyeom Kim

Byoung Hoon Yoon

Joo Hee Lee

Seon Hye Kim

Ki Yong Cheong

Han Hyoung Lee

Ju Eun Kim

Han Jin Lee

Il Chul Kim

Hyojin Yun

Hyun Won Bae

Jin Ah Rho

Lan Huh

Byeong Soo Kim

Jin Geun Choi

Patrice Barre

Nara Kwon

Youn Jae Lee

Hyo Jeong Byun

Hye Ryun Yoo

Sang Kyoum Kim

Ju Hee Seo

Imsang Lee

Moo Young Jung

Hyun-jung Bae

Haena Oh

Hyeryun Yoo

Chang Ii Seo

Goun Park

Hee Su Kwon

Jin-Geun Choi

Hyun-Ju Bong

Jin Seong Rim

Jin Woo Sung

The present disclosure relates to a protein variant having a tryptophan-exporting activity, an L-tryptophan-producing microorganism expressing the protein variant, and a method for producing L-tryptophan using the microorganism.

L-tryptophan-exporting protein variant and method for producing L-tryptophan using the same

The present disclosure relates to a microorganism producing L-tryptophan in which the microorganism is modified such that a protein having an L-tryptophan-exporting activity comprising the amino acid sequence of SEQ ID NO: 1 is expressed, and a method for producing L-tryptophan using the microorganism.

L-tryptophan exporter and method of producing L-tryptophan using the same

Disclosed is a microorganism ofsp. producing O-acetyl homoserine, and a method of producing O-acetyl homoserine in high yield using the microorganism.

Microorganism producing O-acetyl homoserine and the method of producing O-acetyl homoserine using the same

The present disclosure relates to a microorganism producing O-acetylhomoserine with high efficiency and a method for producing O-acetylhomoserine and L-methionine using the microorganism. The present disclosure provides a microorganism producing O-acetylhomoserine having an enhanced activity of a protein which is predicted to export O-acetylhomoserine, and a method for producing O-acetylhomoserine and L-methionine using the microorganism.

Microorganism producing O-acetyl-homoserine and method for producing O-acetylhomoserine using the same

The present disclosure relates to a novel O-acetylhomoserine sulfhydrylase variant, a polynucleotide encoding the same, a vector comprising the polynucleotide, a strain capable of expressing the variant, and a method for producing L-methionine using the variant.

O-acetylhomoserine sulfhydrylase variant and method for producing L-methionine using same

The present invention relates to a quinolinic acid-producing recombinant microorganism expressing a fusion protein of L-aspartate oxidase and quinolinate synthase linked via a linker, and a method for producing quinolinic acid using the same.

Recombinant microorganism producing quinolinic acid and a method for producing quinolinic acid using the same

The present invention relates to a method for producing L-methionine using a bio-synthesis process and a specific enzymatic process. More particularly, the present invention relates to a method for producing L-methionine with high yield by enzyme conversion reaction from L-methionine precursor in the presence of methyl mercaptan (CHSH). The process of the present invention enables selective production of L-methionine which may be used in various fields of industry, such as feed- and food-additives, as raw material for medical supplies, pharmaceutical drugs, and the like.

Preparation of process of L-methionine

A method for the preparation of nicotinic acid, which includes the step of obtaining a culture solution containing quinolinic acid by incubating a microorganism having an ability to produce quinolinic acid, and the step of adding an acid to the culture solution and conducting a decarboxylation reaction.

Method for the preparation of nicotinic acid

To produce quinolinate effectively, a L-aspartate oxidase variant that the feedback regulation by nicotinic acid or NAD is released, and a microorganism including the L-aspartate oxidase variant are provided. Quinolinate may be effectively produced by culturing of the microorganism including the L-aspartate oxidase variant.

L-aspartate oxidase variant and a method for producing quinolinate or nicotinic acid using the same

The present invention relates to a polypeptide that is modified to have homoserine O-acetyltransferase activity, and in particular, the present invention provides a modified polypeptide having homoserine O-acetyltransferase activity, in which the amino acid at position 111 of a polypeptide having homoserine succinyltransferase activity is substituted with other amino acid.

Modified polypeptide having homoserine acetyltransferase activity and microorganism expressing the same

The present invention relates to a novel protein having O-acetylhomoserine sulfhydrylase activity, a mutant protein thereof, a polynucleotide encoding the same, a recombinant vector comprising the polynucleotide, a microorganism transformed with the recombinant vector, and a method for producing methionine or acetic acid using the protein. The production method of the present invention has the advantage of producing L-methionine and acetic acid cost-effectively through having higher conversion rate and reduced reaction time compared to the existing methods, and it can minimize the amount of enzyme homogenate added when using the mutant protein, thereby easily producing L-methionine and acetic acid at high yield.

O-acetylhomoserine sulfhydrylase or mutant protein thereof, and method for converting to methionine using the same

The present invention relates to a method for increasing L-methionine productivity and organic acid productivity. More particularly, the present invention relates to a method which involves adding a mixture containing methyl mercaptan and dimethyl sulfide at a appropriate ratio to O-acetyl homoserine or O-succinyl homoserine and to an enzyme having an activity of converting methionine precursor into L-methionine, so as to perform an enzyme reaction, to thereby improve the conversion rate of L-methionine and organic acid from the L-methionine precursor, and thus increasing L-methionine yield as compared to conventional method.

Method for increasing methionine productivity using a mixture of methyl mercaptan and dimethyl sulfide

Disclosed herein are a microorganism strain capable of producing the L-methionine precursor O-acetyl homoserine in high yield and a method of producing O-acetyl homoserine using the same. The microorganism strain is a strain ofsp. in which an acetyl-CoA synthase gene (acs) and/or a pantothenate kinase gene (coaA) encoding a pantothenate kinase gene refractory to feedback inhibition by CoA is introduced and expressed.

Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism

Disclosed is a strain ofsp., capable of producing O-acetyl homoserine in high yield, with the introduction and enhancement therein of the activity of: homoserine acetyl transferase, aspartokinase and homoserine dehydrogenase; and at least one enzyme selected from a group consisting of phosphoenolpyruvate carboxylase, aspartate aminotransferase and aspartate semi-aldehyde dehydrogenase. Also, a method of producing O-acetyl homoserine using the strain is provided.

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Gyeonggi-do, South Korea

Sung Kwang Son