Sk Biopharmaceuticals Co., Ltd.

Sk Holdings Co., Ltd.

Sung Jin Bae

Sun Gwan Hwang

Tae Sung Koo

So Young Lee

Yeo Jin Yoon

Sang Rak Choi

Jeong Woo Cho

Kyung Chul Cho

Han Ju Yi

Eun Ju Ryu

Sang Mi Chae

Joo Young Park

Hyeon Cheol Gwon

Mo Ses Jeong

A novel methylcyclohexane derivative, and a pharmaceutical composition including the same that is effective for the prevention or treatment of pain.

Methylcyclohexane derivatives and uses thereof

There is provided a pharmaceutical composition for prevention and treatment of restenosis comprising isoxazole derivatives. The pharmaceutical composition includes a therapeutic effective amount of isoxazole derivatives represented by Formula 1 or pharmaceutically available salts thereof. The pharmaceutical composition may be useful to prevent and treat vascular restenosis since the pharmaceutical composition shows an anti-restenosis activity and accelerates the re-endothelization.

Pharmaceutical composition for prevention and treatment of restenosis comprising isoxazole derivatives

Disclosed herein are isoxazole derivatives and uses thereof. Serving as agonists of Wnt, the isoxazole derivatives activate Wnt/&#x3b2;-catenin signaling and thus can be used in the treatment and prevention of diseases related to the signal transduction. Also, pharmaceutically acceptable salts of the isoxazole derivatives are disclosed.

Isoxazole derivatives and use thereof

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Daejeon, South Korea

Sung Jin Bae