Kansas State University Research Foundation

Other

Sung I Koo

Kathy L Gross

Duy H Hua

Kevin Q Owen

Sang K Noh

Compounds affecting cholesterol absorption

The present invention provides a method for increasing the intestinal (lymphatic) absorption, cellular concentration, biliary secretion, hepatic storage, and/or liver concentration of a fat soluble vitamin in a post-menopausal woman. The method comprises orally administering to a post-menopausal woman in need thereof, a fat soluble vitamin and a fat soluble vitamin absorption increasing effective amount of L-carnitine. The L-carnitine enhances the antioxidant defense mechanism and lowers the risk of certain degenerative diseases, such as coronary heart disease, age-related macular degeneration, osteoporosis, cancer, and Alzheimer's, in post-menopausal women. The invention also provides a method for increasing the intestinal absorption of a fat soluble vitamin in an animal. The method comprises orally administering to the animal in need thereof, a fat soluble vitamin and a fat soluble vitamin absorption increasing effective amount of L-carnitine.

Method for increasing intestinal absorption of fat soluble vitamins in post-menopausal women and lower animals

A method and composition for reducing the intestinal absorption of cholesterol in humans or animals are provided. Broadly, the methods comprise ingesting a composition (or a food product including the composition) comprising a substituted phosphatidylcholine compound, or comprising sufficient quantities of a phosphatidylcholine compound to provide from about 20-70% by weight of C,or higher alkyl groups. Preferred substituted phosphatidylcholine compounds include monoether phosphatidylcholines, diether phosphatidylcholines (wherein the alkyl group bonded to the second carbon atom of the glycerol moiety is a C,or higher alkyl group), or ester or diester phosphatidylcholines. Preferred C,or higher alkyl groups include C,-C,alkyl groups, preferably bonded to the second carbon atom of the glycerol moiety of the phosphatidylcholine compound.

Phosphatidylcholine compositions and methods for lowering intestinal absorption and plasma levels of cholesterol

Growing community of inventors

Manhattan, KS, United States of America

Sung I Koo