Nihon Kohden Corporation

Tokyo Women's Medical University

Kowa Company Limited

Waseda University

Sunao Takeda

Takahiro Shioyama

Akane Suzuki

Hirotsugu Kubo

Naoki Kobayashi

Katsuyoshi Suzuki

Teruo Okano

Tatsuya Shimizu

Yoshihiro Sugo

Mitsuhiro Oura

Takeshi Akiyama

Keisuke Uchida

Akihiko Uchiyama

Yoshio Sakai

Hideo Ozawa

Takashi Usuda

Jun Motogi

Yo Kato

Nae Hinata

Kenji Yanashima

Hiroshi Kubota

Teiji Ukawa

Shinji Yamamori

Akihiro Fujita

Takuo Aoyagi

Mitsushi Hyogo

Michio Kanemoto

Kenichi Nomura

Masayoshi Fuse

Yuji Haraguchi

Itaru Yoshizawa

Cheng-tai Xie

Yoshinobu Nakae

Yoshiaki Takamura

Go Taguchi

Takuro Yokoyama

Keitkitsu Ogawa

Haruka Okino

Shigeru Hiraide

Hiromichi Mohri

Makoto Nakai

Suzuki Akane

A cell analyzer includes: a measuring portion which measures cells that are nuclear stained; a displaying portion which displays a histogram of a fluorescence intensity by using a result of the measurement by the measuring portion; and a determining unit which obtains a number of strong-area cells that are distributed in an area where the fluorescence intensity is stronger than normal cells, and which determines a malignancy grade of cancer based on the number of strong-area cells and the histogram.

Cell analyzer and cell analyzation method

A cell culture apparatus includes: an isolator in which a sterile space accommodating a cell incubator filled with a culture solution containing cells to be cultured is disposed; a sampling unit configured to sample the culture solution in the cell incubator; a delivery flow path through which an inside of the sterile space and an outside of the sterile space communicate with each other, the delivery flow path configured to limit a flow in the delivery flow path to a direction that is directed from the inside of the sterile space toward the outside of the sterile space; and a culture solution delivering section configured to deliver the sampled culture solution to the outside of the sterile space via the delivery flow path.

Cell culture apparatus

A method of analyzing cells, the method comprising: measuring a number of cells which are nuclear stained, in a to-be-determined tissue, and acquiring a histogram showing a fluorescence intensity based on a result of the measurement; analyzing the histogram, and acquiring data of predetermined parameters; comparing the data of the parameters with first thresholds predetermined for the parameters, to perform a first cancer determination for each of the parameters on the to-be-determined tissue; performing a scoring process for each of the parameters, on a result of the first cancer determination for each of the parameters, to calculate scores of the parameters; and combining the scores of the parameters with one another, thereby performing a second cancer determination on the to-be-determined tissue.

Method and apparatus for analyzing cells

A cell analyzing apparatus includes: a histogram acquirer which is configured to perform measurement of a number of nuclear stained cells, and which, by using a result of the measurement, is configured to acquire a histogram indicating a fluorescence intensity; and an analysis controller which is configured to apply frequency analysis on data of the histogram acquired by the histogram acquirer, and which is configured to determine existence/nonexistence of cancer cells based on a result of the frequency analysis.

Cell analyzing apparatus and cell analyzing method

A cell analyzing apparatus includes: a first histogram acquiring section which is configured to acquire a first histogram of fluorescence intensities by using a result of a measurement of a number of nuclear stained cells; a second histogram acquiring section which is configured to acquire a second histogram that is normalized based on a fluorescence intensity value indicating a maximum value of the first histogram; a determining section which is configured to determine whether cancer cells exist or not, based on one of the first histogram and the second histogram; and an outputting section which is configured to output a result of the determination performed by the determining section.

A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.

Method and apparatus for measuring PH of solution

A pH measuring method includes: illuminating a medium solution, which includes: a first material; and a second material, with a plurality of light beams, which includes: a first light beam, a wavelength of which corresponds to a first absorption peak; a second light beam, a wavelength of which corresponds to a second absorption peak or a second convergence point; a third light beam, a wavelength of which corresponds to a third absorption peak or a third convergence point; and a fourth light beam, a wavelength of the fourth light beam at which an absorbance of at least one of the first and second materials is converged irrespective of a pH; receiving transmitted or reflected light beams of the first to fourth light beams; measuring absorbances at the wavelengths of the received light beams respectively; and calculating a pH of the medium solution based on the absorbances.

Method and apparatus for measuring pH of medium solution

A method of calculating a blood pressure, includes: providing a non-invasive blood pressure measurement apparatus which includes a cuff being inflatable and deflatable and adapted to be fitted on a part of a living body and in which a plurality of calculation methods each of which has priority in accordance with a type of noise information are set; detecting, by the cuff, a signal waveform representing a change in an oscillation amplitude and a change in a cuff pressure; determining the type of the noise information contained in the detected signal waveform; deciding the blood pressure from at least one candidate value for the blood pressure, which is calculated by one of the calculation methods that has the priority with respect to the determined type of the noise information; and displaying the decided blood pressure.

Blood pressure calculation method for non-invasive blood pressure measurement apparatus

A cell isolation apparatus includes: a chamber body which includes a chamber into which tissue is to be introduced; an isolation member which is moved in the chamber and which is to collide with the tissue to isolate a cell; and a controlling portion which controls an operation of the isolation member in the chamber body.

Cell isolation apparatus

In order to measure a pulse rate and an oxygen saturation of a subject who is in an exercised state, each of two pulse wave signals obtained from the subject is separated into a signal component and a noise component. A frequency spectrum of the signal component and a frequency spectrum of the noise component are obtained. It is judged whether a body motion of the subject is occurred based on the frequency spectrum of the signal component and the frequency spectrum of the noise component. A pulsation frequency is determined based on the judgment as to the body motion. The pulse rate is calculated based on the pulsation frequency. The oxygen saturation is calculated based on a ratio of spectra of the two pulse wave signals corresponding to the pulsation frequency.

Method and apparatus for measuring pulse rate and oxygen saturation achieved during exercise

A cell isolation apparatus includes: a cylinder member that is inserted into a container into which a reagent is to be introduced; a net which is stretched over the cylinder member; a tissue acquiring unit that is projected from the cylinder member; and a bottom lid portion that is configured by a bottomed pipe in which a first hole that communicates an interior with an exterior is formed, and that is fitted to a bottom portion of the cylinder member in a state where the net and the tissue acquiring unit are accommodated.

A tonometry device includes a contact device for contacting the object, means for vibrating the contact device and the object, means for applying a voltage to the vibration means, means for measuring a current flowing through the vibration means, and an information processing means. The information processing means determines two resonance points of the device and the measured object by measuring current through the system at a plurality of vibrational frequencies. The information processing means then determines the internal pressure of the object by determining that a first pressure is higher than a second pressure by determining that the first pressure has a lower measured current than the second pressure at frequencies outside of the range of frequencies between the resonance points, and that the first pressure has a higher measured current than the second pressure at frequencies within the range of frequencies between the resonance points.

Pressure measuring method, pressure measuring device, and tonometer

A first member is adapted to measure an electrocardiogram of a patient. A second member is adapted to measure a peripheral pulse wave of the patient. A first calculator calculates a pulse wave propagation time (PWTT) and a heart rate (HR) of the patient based on the electrocardiogram and the peripheral pulse wave. A second calculator calculates a cardiac output (CO) of the patient with an equation of CO=(&#x3b1;K&#xb7;PWTT+&#x3b2;K)&#xb7;HR, where &#x3b1;, &#x3b2; and K are coefficients inherent to the patient.

Method and apparatus for measuring blood volume, and vital sign monitor using the same

An intraocular tension measuring method comprising vibrating an eyeball to be examined by a sound wave, measuring vibration of the eyeball to be examined by a noninvasive means to determine a Q value of resonance of the eyeball to be examined, and calculating intraocular tension from the Q value, and an intraocular tension measuring device comprising a vibrating means for vibrating an eyeball to be examined by a sound wave, a measuring means for noninvasively measuring vibration of the eyeball to be examined, a Q value calculating means for calculating a Q value of resonance of the eyeball to be examined from the vibration measured by the measuring means, and an intraocular tension calculating means for calculating intraocular tension from the Q value.

Method and device for measuring intraocular tension

Growing community of inventors

Tokyo, Japan

Sunao Takeda