Korea Research Institute of Chemical Technology

Seoul National University

Sun-Hyun Park

Ki-Suk Kim

Jae-Hyeok Lee

JinJu Park

Seong-Hoon Park

Jae-Meun Lee

Ji Yeoun Lee

A clearing pretreatment method of a biological sample having a size of at most 1 mm, that is, a spheroid or organoid, according to the present invention uses a phosphate-buffered saline (PBS) rather than a conventional sucrose solution as a pretreatment solution, thus solving the problem in which the spheroid or organoid floats above the surface of water due to the density difference such that the structure of the sample is damaged. Therefore, there is an effect in that the spheroid or organoid can be transparentized while maintaining the original shape thereof, thus making it possible to image deep parts.

Transparentizing pretreatment method of biological sample having size of at most 1 mm, and transparentizing method of biological sample including same

The present invention relates to a water degradable film comprising hyaluronic acid or a salt thereof and polyphenol compounds. The film of the present invention can transcribe nanofilms in the form of CNT (carbon nanotube), graphene and magnetic particles to various places. The film of the present invention can be dissolved by an aqueous solution or body fluid, and can be effectively used in the medical field since it is non-toxic and biocompatible. The film of the present invention can also be effectively used as a transcript that does not degrade the quality and performance of the device because no residue remains in the electronic device and the existing photolithography process.

Water degradable film containing hyaluronic acid or salt thereof and polyphenol compounds

Growing community of inventors

Daejeon, South Korea

Sun-Hyun Park