Kbnp, Inc.

Biopoa, Inc.

Sun-Hee Cho

Tae-Eun Kim

Sun-Joong Kim

Tae-Hwan Kim

Chae-Hyun Kim

Hyuk-Joon Kwon

Young-Ho Park

Il-Hwan Kim

Jang-Hyuck Han

Young-Jin An

Young-Jin Ahn

Mi-Joung Ko

The present invention relates to a recombinant vector for transcription of the Newcastle disease virus (NDV) genome, a strain of attenuated recombinant NDV with a surface antigen of pathogenic NDV prepared by the vector, a method of preparing a recombinant NDV having low pathogenicity and high protectivity efficiency against Newcastle disease (ND) using the vector, and a vaccine against ND containing the recombinant NDV.

Attenuated recombinant newcastle disease virus and vaccine containing the same

The present invention relates to an epitope of HN protein in Newcastle disease virus which can be recognized by an avian immune system and an antibody against the epitope, a method for detecting a Newcastle disease virus by using the antibody, and an antigenic variant of Newcastle disease virus carrying changes in the epitope. The epitope of HN protein and the antigenic variant of Newcastle disease virus can be used for developing efficient vaccines, and further, in diagnosing the Newcastle disease virus rapidly and exactly.

HN epitope recognized by avian immune system and antigenic variant newcastle disease viruses carrying changes in the epitope

Growing community of inventors

Seongnam-si, South Korea

Sun-Hee Cho