Korea Research Institute of Bioscience and Biotechnology

Samsung Electronics Co., Ltd.

Seoul National University

Snu Rdb Foundation

Sun Gun Chung

Sung Sup Park

Kwang-Pyo Lee

Seung Min Lee

Sang Chul Park

Young Hoon Son

Ki Sun Kwon

Kwang Pyo Lee

Eun Soo Kwon

Ki-Sun Kwon

Jeong Yi Choi

Jeongi Choi

Sung Chun Cho

Jung Yi Choi

The present invention relates to sobrerol or a pharmaceutically acceptable salt thereof, which can promote differentiation of myoblasts to form myotubes, thereby preventing muscle weakness and effectively improving muscle functions. Therefore, the pharmaceutical composition containing the same can be effectively used for preventing or treating muscle weakness related diseases.

Composition for preventing or treating muscle weakness-related diseases comprising sobrerol

The present invention relates to A method for promoting the differentiation of myoblasts comprising treating myoblasts with butylpyridinium, a derivative thereof, or a pharmaceutically acceptable salt thereof; a method for strengthening muscles comprising administering butylpyridinium, a derivative thereof, or a pharmaceutically acceptable salt thereof to a subject in need thereof; a feed or feed additive for strengthening muscles comprising butylpyridinium, a derivative thereof, or a pharmaceutically acceptable salt thereof; a method for treating a disease associated with muscle weakness comprising administering butylpyridinium, a derivative thereof, or a pharmaceutically acceptable salt thereof to a subject in need thereof.

Pharmaceutical composition for preventing or treating muscle weakness-related diseases, containing butylpyridinium or derivative thereof

The present invention relates to a pharmaceutical composition for preventing or treating a muscle wasting-related disease comprising diaminodiphenylsulfone (Dapsone; DDS) or a pharmaceutically acceptable salt thereof as an active ingredient. The composition according to the present invention may be effectively used to prevent or treat a muscle wasting-related disease by increasing muscle mass, preventing muscle loss and effectively restoring muscle function.

Pharmaceutical composition for preventing or treating muscle wasting-related disease comprising diaminodiphenylsulfone or pharmaceutically acceptable salt thereof

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Seoul, South Korea

Sun Gun Chung