Life Technologies Corporation

Sumonto Ghosh

Robert Setterquist

Wade Lukianow

Timothy Barta

Alexandre Vlassov

Robert Smith

Justin Inslee

Ethan Gentert

Jason Jones

Christopher Crowley

Jay Greco

Sara Thiele

Carolyn Adams

Kraig Kruger

David Cerrone

Brian Vajda

Andrew Basta

Allan Evans

Anne Cox

Mark Mayernick

Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Systems, methods, and devices for automated nucleic acid and protein isolation

Growing community of inventors

Longmont, CO, United States of America

Sumonto Ghosh