Biocon Limited

Sumithra Srinath

Sambasivam Ganesh

Tom Thomas Puthiaparampil

Madhavan Sridharan

Tom Thomas Puthiaprampil

Ravindra Chandrapa

Joy Matthew

The present invention relates to a novel process for the preparation of the HMG-CoA reductase inhibitor, fluvastatin, more specifically to a process for the preparation of amorphous form of fluvastatin sodium.

Process for the preparation of amorphous fluvastatin sodium

A novel process of the preparation of amorphous atorvastatin calcium starting from a compound of Formula (II).

Process for the production of amorphous atorvastatin calcium

In one aspect, the present invention provides a novel process for the preparation of tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate, a key intermediate for the preparation of HMG-CoA reductase inhibitor.

Process for the preparation of tert-butyl 6-cyano-5-hydroxy-3-oxohexanoate

The present invention relates to optically active boronate derivatives which are useful as intermediates for the synthesis of HMG-CoA enzyme inhibitors such as atorvastatin, cerivastatin rosuvastatin, pitavastatin, and fluvastatin.

Boronate esters

The present invention relates to optically active boronate derivatives which are useful as intermediates for the synthesis of HMG-CoA enzyme inhibitors such as atorvastatin, cerivastatin, rosuvastatin, pitavastatin, and fluvastatin.

Growing community of inventors

Bengaluru, India

Sumithra Srinath