Evotec Ag

Renovis, Inc.

Evotec (us) Inc.

Second Genome, Inc.

Sumithra Gowlugari

John Kincaid

Carl J Kaub

Yeyu Cao

Zhan Wang

Michael G Kelly

Yunfeng Fang

Zhi-Liang Wei

Jianhua He, Legal Representative

Carl Kaub

Compounds are provided according to formula 1: where A, B, W, X', L, R, R, R, and m&#x2032; are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.

Amide compounds, compositions and uses thereof

Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Bicycloheteroaryl compounds as P2X7 modulators and uses thereof

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Compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.

Growing community of inventors

San Mateo, CA, United States of America

Sumithra Gowlugari