Hemasure, Inc.

Sumith Ranil Wickramasinghe

Stephen B Kessler

Franco Castino

A method for removing tumor cells from tumor cell-contaminated stem cell products is disclosed. One embodiment of the method relies on an in-line filtration device that includes a tumor cell reduction filter means, preferably comprised of one or more tumor cell reduction filter pads. The tumor cell reduction filter means provides at least a ten-fold reduction in tumor cells while allowing for at least a 30% recovery of stem cells in a filtered stem cell product.

Method and apparatus for removing tumor cells from tumor cell-contaminated stem cell products

Improved devices for blood separations are provided based on the use of hollow fiber membrane arrays in extra-lumenal crossflow filtration. Blood is processed extra-lumenally across an ordered array of microporous hollow fibers to separate cells from plasma. By use of extra-lumenal crossflow filtration with suitably oriented fibers, the separation device is more efficient than existing devices which benefits a patient or donor by reducing extracorporeal volume.

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Marlborough, MA, United States of America

Sumith Ranil Wickramasinghe