Zenyaku Kogyo Kabushiki Kaisha

Sumio Terada

Tetsuo Watanabe

Toshiaki Suzuki

Kenichi Saito

Kenichi Saitoh

Seiichiro Kawashima

Hiroya Sasahara

Naoto Noguchi

Toshihisa Kanda

Takashi Ishida

Tsuneo Inoue

Kikuo Itoh

Mitsuo Sakato

Components that demonstrate an &#x3b1;-glucosidase inhibitory activity and hyperglycemic inhibitory activity have clearly been provided from among the components included in Yacon. The present inventors found that as a result of screening for a strong anti-oxidant component in a Yacon aerial portion extract, an antioxidant activity was converged in a DIAION HP-20 column chromatography 50% methanol-eluted fraction of hot water extract. Thus, since a previously unidentified high-content component was confirmed, the present inventors conducted purification thereof, and thereby separated TCAA. As a result, this TCAA was found to be the component that demonstrates the &#x3b1;-glucosidase inhibitory activity and hyperglycemic inhibitory activity.

Functional food containing sodium tricaffeoylaldarate

An O-aryl N-(6-alkoxy-2-pyridyl)-N-alkylthiocarbamate represented by the following formula (I): (wherein R, Rand Ar are as defined below) is produced by treating a phenol represented by the following general formula (IV):Ar&#x2014;OH&#x2003;&#x2003;(IV)(wherein Ar represents an aryl group) with a base in a solvent and then adding thereto an alkali metal salt of N-(6-alkoxy-2-pyridyl)-N-alkyldithiocarbamic acid represented by the following general formula (III): (wherein Rand Rindependently represent a C-Calkyl group and M represents an alkali metal) and a halomethane represented by the following general formula (V):CHXY&#x2003;&#x2003;(V)(wherein X and Y represent different halogen atoms, m represents 0, 1 or 2, n represents 0, 1 or 2, and m+n equals 2) for causing a reaction.

Method for producing thiocarbamate derivative

Quinoline sulfide derivatives

Growing community of inventors

Nerima-ku, Japan

Sumio Terada