Vyome Therapeutics Limited

Vyome Biosciences Private Limited

Vyome Biosciennces Pvt. Ltd.

Vyome Biosciences Pvt. Ltd.

Sumana Ghosh

Shiladitya Sengupta

Suresh Sadhasivam

Anamika Bhattacharyya

Shamik Ghosh

Nilu Jain

Sudhanand Prasad

Richard Buchta

Suresh Rameshlal Chawrai

Suresh Chawrai

Rajesh Sudhir Gokhale

Nidhi Arora

Sayali S Shah

Mau Sinha

D Sreedhar Reddy

Siva Ganesh Mavuduru

Mallika Mishra

Nupar Tandon

Kirti Bajaj

Deepak Kumar

Abhijit S Bapat

Gauthami Mahesh

Debabrata Mandal

The present disclosure relates generally to novel molecules, compositions, and formulations for treatment of bacterial infections in general and more specifically to bacterial infections with antibiotic resistant pathogens.

Treatments for resistant acne

Antibacterial therapeutics and prophylactics

The present invention is directed to anti-fungal compositions comprising an anti-fungal agent, an oil and excipients or additives. The compositions of the present invention are devoid of C-11 or greater fatty acids/esters.

Topical oil composition for the treatment of fungal infections

The invention provides conjugate-based antifungal or antibacterial prodrugs formed by coupling at least one anti-fungal agent or antibacterial agent with at least one linker and/or carrier. The prodrugs are of formula: (i) (AFA)-X-(L); (ii) [(AFA)-X]-L; (iii) AFA-[X-(L)]; or (iv) (AFA)-X, wherein: AFA is an antifungal agent or an antibacterial agent; L is a carrier; X is a linker; m ranges from 1 to 10; n ranges from 2 to 10; m' is 1 to 10; p is 1 to 10; n&#x2032; is 1 to 10; and q is 1 to 10, provided that q&#x2032; and n are not both 1; and m&#x2033; is 1 to 10. The invention also provides nanoparticles comprising the conjugate-based prodrugs. Additionally, the invention also provides non-conjugated antifungal and antibacterial agents in the form of nanoparticles.

Conjugate-based antifungal and antibacterial prodrugs

Growing community of inventors

Delhi, India

Sumana Ghosh