Grand Theravac Life Sciences (Nanjing) Co., Ltd.

Sulin Ren

Jun Ge

Jianqiang Li

Tong Zhou

Jiaojiao Sun

Xiaoxiao Chen

Hongying Huang

Yue Gu

Honglin Sun

Shiwei Wang

Jingfeng Huang

Yue Chen

Xiaodong Wang

Xue Zhou

A pharmaceutical composition comprising: i) a herpes gE protein, an active fragment of the protein, a variant of the protein, or a mixture of at least two of them; ii) an immunostimulatory composition comprising a saponin and a CpG oligodeoxynucleotide, or consisting of an adjuvant comprising a saponin and a CpG oligodeoxynucleotide. Use of the pharmaceutical composition in the preparation of a medicament for preventing and/or treating a varicella-zoster virus infection and/or a varicella-zoster virus mediated disease. The pharmaceutical composition achieves an unexpected technical effect and can mediate a stronger immune response.

Pharmaceutical composition and use thereof

The present invention discloses a pharmaceutical preparation for treating hepatitis B, a preparation method and use thereof. The pharmaceutical preparation comprises a solution of hepatitis B surface antigen, further a solution of hepatitis B core antigen, and furthermore an oligodeoxynucleotide solution. The pharmaceutical preparation is free of saccharide, has a simple composition and a good antigen stability, without the adverse reactions caused by aluminum adjuvants, and shows good preservation effects in long-term stability experiments.

Pharmaceutical preparation for treating hepatitis b, preparation method therefor and use thereof

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Nanjing, China

Sulin Ren