Council of Scientific and Industrial Research

Other

Zandu Pharmaceutical Works Ltd.

Sukhdev Swami Handa

Naresh Kumar Satti

Krishan Avtar Suri

Vikram Bhardwaj

Subhash Chandra Taneja

Rakesh Maurya

Bal Krishan Chandan

Vishwa Nath Gupta

Om Parkash Suri

Surrinder Koul

Ghulam Nabi Qazi

Kasturi Lal Bedi

Anamika Khajuria

Jawahir Lal Koul

Om Prakash Suri

Anpurna Kaul

Ulhas Salunkhe

Bupinder Singh

Asha Bhagat

Rajinder Singh

Beenu Moza

Girish G Parikh

Raman Krishnamurthy

Prabhakar Kulhar

Ajit Kumar Saxena

Vijeshwar Verma

Bupinder Singh Jaggi

Kanaya Lal Dhar

Lila Ram Manahas

Om Prakash Gupta

Anil Prabhakar

A S Anand

S K Banerjee

V N Gupta

J L Suri

A K Saxena

Ram Vilas Parsad Sinha

Deepak Mundkinajeddu

Rajinder Kumar Khajuria

Deepa Singh

Om Parkash Gupta

Rajinder Parshad

Ravi Ji Kotru

Zabeer Ahmed

Kuldeep Kumar Gupta

Bhupinder Singh

The present invention relates to novel compounds possessing specific hot, pungent and spicy taste when subjected to direct pungency evaluation, which may be useful as food additives and anti-oxidants, however the said compounds do not add to any nutritional value but the synthesised compounds can possess useful pharmacological properties which is expected to find application in new test models for the development of anti-inflammatory drugs, bioavailability enhancers and for the study of hepatic drug metabolising mechanism; also relates to a process for preparing the said compounds.

Substituted aryl alkenoic acid heterocyclic amides

The present invention relates to a pharmaceutical composition comprising a bioactive constituent trans-tetracos-15-enoic acid and a process for the isolation of tetracos-15-enoic acid from the plantalong with a method of treatment for hepatotoxicity.

Pharmaceutical composition and process for isolation of trans-tetracos-15-enoic acid and method of treatment for hepatotoxicity

The present invention relates to a process of isolation of bioactive eupalitin (3-O-O-D-galactopyranoside) of formula 1 possessing anti-osteoporosis activity by extraction of powdered leaves of, with better yield:

Process for isolation of eupalitin from Boerhavia diffusa

The present invention relates to a synergistic hepatoprotective pharmaceutical composition comprising an effective amount of trans-tetracos-15-enoic acid (TCA) and Apocynin (APO), the present invention also relates to a method of treatment for hepatotoxicity in mammals and humans.

Synergistic composition of trans-tetracos-15-enoic acid and Apocynin and method of treatment for hepatotoxicity

The present invention relates to a process for isolating plantextract that contains flavonoid glycoside, wherein the extract possesses hypoglycaemic activity. The present invention also contemplates a composition containing the extract and a method of treating various hyperglycaemic conditions including non-insulin dependent diabetes mellitus disease condition by administering the extract.

Method of treating diabetes using plant argyrolobium roseum extract, and a process for the isolation of extract from the said plant

The present invention relates to a process for the preparation of trans-alkenoic acids of general formula CH&#x2014;(CH)n&#x2014;CH&#x2550;(CH)mCOH where n=4 to 9 m=8 to 16. More particularly, the present invention relates to a process for the preparation of trans-tetracos-15-enoic acid, which is a bioactive constituent possessing dose-related hepatoprotective activity. The present invention also relates to the use thereof for hepatoprotection.

Process for the synthesis of trans-alkenoic acids, use thereof

The present invention relates to a novel compound 8-(C-&bgr;-D-glucopyranosyl)-7,3&prime;,4&prime;-trihydroxyflavone, isolated from useful in the treatment of diabetes. The present invention also relates to a method for the preparation of the compound and to the uses thereof.

8-(C-&bgr;-D-glucopyranosyl)-7, 3', 4'-trihydroxyflavone, process of isolation thereof, pharmaceutical composition and method for the treatment of diabetes

The present invention relates to a process for the isolation of a novel oligospirostanoside structurally constructed as 3-0-&lsqb;&agr;-L-rhamnopyranosyl-(1&rarr;2)-&agr;-L-rhamnopyranosyl-(1&rarr;4)-0-&bgr;-D-glucopyranosyl&rsqb;-25(S)-5&bgr; spirostan-3&bgr;-ol isolated from and biologically evaluated as a potent immunomodulatory agent.

Process for the isolation of novel oligospirostanoside

The present invention provides a synergistic composition of bioactive fraction essentially constituting iridoid glucosides, acetyl barlerin and shanzhiside methyl ester isolated from a plant source along with a process for the isolation of the bioactive fraction, the present invention also relates to a method of treating mammals and humans for hepatotoxicity, stress and immuno-deficiency with the synergistic bioactive composition.

Synergistic composition of bioactive fraction isolated from barleria prionitis linn and a method of treatment for hepatotoxicity, immuno-deficiency and fatigue and a process thereof

The present invention relates to a novel oligospirostanoside having the structure 3-0-&lsqb;&agr;-L-rhamnopyranosyl-(1&rarr;2)-&agr;-L-rhamnopyranosyl-(1&rarr;4)-0-&bgr;-D-glucopyranosyl&rsqb;-25(S)-5&bgr;-spirostan-3&bgr;-ol isolated from and to a pharmaceutical composition containing the novel oligospirostanoside and to a method for immunomodulation using said oligospirostanoside by administering a pharmaceutically effective amount of said novel oligospirostanoside.

Oligospirostanoside, pharmaceutical composition containing novel oligospirostanoside and method for immunomodulation using said oligospirostanoside

Glucopyranoside and process of isolation thereof from pterocarpus marsupium pharmaceutical composition containing the same and use thereof

The present invention relates to a composition useful for early and profuse sporulation in fungi with about 100 fold increase in spore count within 48 hours of inoculation, said composition comprising molasses ranging between 5-20 g/L, Corn Steep Liquor (CSL) ranging between 10-25 g/L, Sodium chloride (NaCl) ranging between 5-15 g/L, calcium sulphate (CaSO ) ranging between 0.1-0.5 g/L, Potassium dihydrogen phosphate (KH PO ) ranging between 0.001-0.01 g/L, Magnesium sulphate (MgSO .7 H O) ranging between 0.001-0.01 g/L, Copper sulphate (CuSO ) ranging between 0.001-0.0050 g/L, Ferrous sulphate (FeSO ) ranging between 0.0009-0.005 g/L, an anti-foam agent, and optionally solidifying agent and a method thereof.

Composition for early and profuse sporulation in fungi and a method thereof

Glucopyranoside, process for isolation thereof, pharmaceutical composition containing same and use thereof

This invention discloses a process for the use of a novel organism belonging to the genus Trichosporon sp. as whole wet or dry cell culture or cell free extract or crude enzyme or pure isolated enzyme The strain of Trichosporon sp. used in the process is designated as RRLY-15 and has been deposited in Deutsche Sammlung von Mikroorganismen und Zellekulturen GmbH (DSMZ). The invention also discloses the preparation of S(&plus;)-6-methoxy-2-naphthalene acetic acid (naproxen) of formula (2) through enantioselective hydrolysis of a racemic mixture of alkyl esters of (&plusmn;)-6-methoxy-&agr;-methyl-2-naphthalene acetic acid of formula (1) where R represents &mdash;CH,,&mdash;C,H,,&mdash;C,H,,&mdash;C,H,and the like and S(&plus;)- Naproxen is a medicinally important non steroidal anti-inflammatory drug.

Trichosporon sp RRLY-15 (DSM 11829) and its use to prepare S(&plus;)-6-methoxy-methyl-2-naphthalene acetic acid

Growing community of inventors

Jammu, India

Sukhdev Swami Handa