Pierce Biotechnology, Inc.

Life Technologies Holdings Pte Limited

Cellomics, Inc.

Dyomics Gmbh

Suk Hong

Brian Webb

Eric Leigh Hommema

Nikki L Jarrett

Kok Siong Teo

Benyong Shi

Yanpeng Cao

Surbhi Desai

Matthias S Wenzel

Peter T Czerney

Frank G Lehmann

Boguslawa Dworecki

Greg Hermanson

Tiong Han Toh

Richik Niloy Ghosh

Kelli D Feather-Henigan

Steven Yeo

Jason Aravich

Rachael Mae Berry

A method to maximize use of the field of view for an imaging system is provided herein. An imaging device can be part of the imaging system and include a detection unit and an alignment unit. The method includes capturing an initial image of an object and then calculating a rotational angle and zoom factor for the object in order to maximize the object's footprint within the field of view. Once the calculations are complete a computer can instruct the detection and alignment units to reconfigure their orientations relative to the object.

Systems, methods, and apparatuses for optimizing field of view

A method for creating a projected image including capturing an image of an item or data relating to an image of an item with an image capture device having a plurality of light sensing units, at a first exposure time. The method further includes receiving as an input or determining a second exposure time, and creating a projected image of the item at the second exposure time based upon the captured image or the captured data relating to the image.

Method and system for projecting image with differing exposure times

Systems and methods generate a projected image at an optimal exposure time. Images are captured different exposure times. Pixels that satisfy an intensity threshold percentage for each image are selected. The intensity values of the selected pixels are then evaluated to determine whether the selected pixels are distributed above a lower intensity threshold and below an upper intensity threshold. The linear relationship is projected to determine an optimal exposure time that has an optimal exposure time duration that exceeds each exposure time duration associated with each of the captured images when the linear relationship exists between each of the captured images. A projected image associated with the optimal exposure time is generated from one or more of the captured images.

A method and system to enhance analysis of electrophoretic bands by overlaying only the pixels of interest. The overlaid pixels are superimposed as a layer above, i.e., in the foreground of, the overlaid image, i.e., in the background. A user employs the superimposed pixels for molecular weight determination and is still able to generate densitometry analysis of the remaining pixels in the overlaid image.

Analysis of electrophoretic bands in a substrate

A phosphine derivative of DyLight dyes modified with ethylene glycol or (poly)ethylene glycol groups. In one embodiment, the compounds are useful in chemoselective ligation reactions.

Phosphine derivatives of fluorescent compounds

A method of predicting cell toxicity of a compound includes imaging cells positioned within a plurality of containers to obtain imaged cellular targets, each container being treated with a different concentration of the compound, the imaging being performed using a quantitative high-content cell imaging system; quantitatively measuring the imaged cellular targets to detect changes in multiple cellular targets associated with cytotoxicity of the compound; and analyzing measurements obtained from the measured imaged cellular targets over a range of compound concentrations to determine the toxicity of the compound.

Predicting toxicity of a compound over a range of concentrations

A method of predicting hepatotoxicity of a compound. The method includes imaging cells of hepatic origin positioned within a plurality of containers to obtain imaged cellular targets, each container being treated with a different concentration of the compound, the imaging being performed using a quantitative high-content cell imaging system; quantitatively measuring the imaged cellular targets to detect changes in multiple cellular targets associated with cytotoxicity of the compound; and analyzing measurements obtained from the measured imaged cellular targets over a range of compound concentrations to determine the hepatotoxicity of the compound.

Growing community of inventors

Roscoe, IL, United States of America

Suk Hong