Samyang Corporation

Sujung Lee

Chaul Min Pai

Chaul-Min Pai

Sung-Bum La

Moon Gun Seo

Bo-Youn Seo

Chang-Baeg Lim

Heenam Park

Seung-Seo Lee

Chang Baeg Lim

Seung Seo Lee

In Park

A colonic drug delivery composition contains a first polysaccharide and a second polysaccharide wherein both polysaccharide are degradable by colonic enzymes and are mixed at a environmental pH of about 7 or above, without use of a cross-linking agent. A colon selective pharmaceutical composition and dosage form for oral delivery of a drug, diagnostic reagent, or mixture thereof includes the drug, diagnostic reagent, or mixture thereof in contact with the polysaccharide composition. A method of preparing such a colonic drug delivery composition and the colon selective pharmaceutical composition and dosage from are also disclosed.

Composition and pharmaceutical dosage form for colonic drug delivery using polysaccharides

A composition comprising gelatin and a polysaccharide which is degradable by a colonic enzyme and, optionally, with an aldehyde and/or a polyvalent metal ion and/or an additional polysaccharide, which is not degraded or disintegrated in the upper gastrointestinal tract, thereby rendering the active substance loaded therein to be selectively delivered to the colon and to be effectively released in the colon.

Colon selective drug delivery composition

Growing community of inventors

Taejon-si, South Korea

Sujung Lee