Samsung Electronics Co., Ltd.

Kolon Life Science, Inc.

Viromed Co., Ltd.

Kolon Tissuegene, Inc.

Sujeong Kim

Minjung Kim

Heonsik Choi

Jong-Mook Kim

Minju Kim

Daewook Kim

Jihun Oh

Kyoungbaek Choi

Hyeonyoul Lee

Min Soo Kim

Hyesun Lee

Juyoung Kim

Sanghune Park

Song Xu

Kyunghoi Koo

Kyoungwon Lee

Jiyeon Park

Daero Kim

Hwanjun Choi

Inmo Kim

Jangjoon Park

Daeseok Byeon

Bongsoon Lim

Sunyoung Kim

Joonsung Kim

Hongsoo Jeon

Kyuhyun Lee

Hyung-Kwon Lim

Woong Hahn

Mijung Lee

Jun-tae Lee

Dong-Sik Kim

Eun Jung Song

Young Seoub Park

Sangyun Hwang

Kisu Kim

Jongwha Won

Jae Chan Park

Taemin Ok

Eun-Hee Lee

Miyoung Oh

Joohee Shin

WonSun Yoo

Taekyung Yeo

Jongho Cho

Eunjin Lee

Jieun Hong

Soondong Lee

Jaeil Shin

Yeomoon Sim

Yejin Kwon

Haesu Kang

Soongyu Choi

Min Kim

Wonsun Yoo

Song Shan Xu

A semiconductor device may include stacks extended in a first direction on a substrate, separation structures extended in the first direction and respectively provided between the stacks, vertical channels penetrating each of the stacks, bit lines extended in a second direction crossing the first direction, each of the vertical channels being overlapped with a pair of the bit lines, and contact plugs connecting the bit lines to the vertical channels. Each of the stacks may include electrodes stacked on the substrate and at least two upper separation patterns dividing an upper one of the electrodes into several portions in the second direction. The vertical channels may be classified into a plurality of types, depending on a distance from one of the separation structures in the second direction, and each of the bit lines may be connected to all types of the vertical channels.

Semiconductor device and electronic system therewith

A method of training a physical interface between a first device and a second device includes performing a first training of the physical interface by communicating with the second device by using a first candidate group of lanes from among a plurality of lanes; performing a second training of the physical interface by communicating with the second device by using a second candidate group of lanes from among the plurality of lanes, the second candidate group being different from the first candidate group; determining a lane group based on a result of the first training and a result of the second training; and setting the second device so that the determined lane group is used for the physical interface.

Apparatus and method for training device-to-device physical interface

A memory controller includes a first receiver configured to compare a read reference voltage with a piece of data received through a first data line and output a first piece of data; a first duty adjuster configured to adjust a duty of the first piece of data; a second receiver configured to compare the read reference voltage with a piece of data received through a second data line and output a second piece of data; a second duty adjuster configured to adjust a duty of the second piece of data; and a training circuit configured to perform a training operation on pieces of data received through a plurality of data lines, to obtain a target read reference voltage for each piece of data and correct a duty of each piece of data based on a level of the target read reference voltage for each piece of data.

Memory controller performing data training, system-on-chip including the memory controller, and operating method of the memory controller

A memory device includes: a memory cell region including gate electrodes spaced apart from each other on a first semiconductor substrate to be stacked, and channel structures; and a peripheral circuit region including upper metal lines disposed above a second semiconductor substrate, disposed below the memory cell region. The first semiconductor substrate includes first regions, having a first value corresponding to a distance between the first semiconductor substrate and the upper metal lines, and second regions having a second value, lower than the first value. A reference voltage for operating the memory device is transmitted to at least one of the first upper metal lines, disposed below the first region. Accordingly, coupling capacitance for a significant signal may be reduced while maintaining a length of a connection portion and the magnitude of resistance of a common source line. Furthermore, an error rate of the memory device may be reduced.

Memory device

An integrated circuit device includes a semiconductor substrate having components of a peripheral circuit structure formed in and on a surface of the semiconductor substrate. The peripheral circuit structure comprising a plurality of protective antenna diodes therein. A memory cell array structure is provided on at least a portion of the peripheral circuit structure. A charge accumulating conductive plate is provided, which extends between the peripheral circuit structure and the memory cell array structure. The conductive plate is electrically connected to current carrying terminals of the antenna diodes within the peripheral circuit structure. The conductive plate may have a generally rectangular planar shape with four corners, and the antenna diodes may be arranged into four groups, which extend between respective corners of the conductive plate and the semiconductor substrate.

Integrated circuit device with protective antenna diodes integrated therein

The present invention relates to a recombinant vaccinia virus in which the expression of some genes is inhibited, and a use thereof. The recombinant vaccinia virus of the present invention selectively kills cancer cells, and has an excellent reproducibility in cancer cells. Also, the virus has a lower toxicity to normal cells, and thus has an advantage of being safe for a human body. Therefore, the recombinant vaccinia virus of the present invention can be effectively used as a composition for treating cancer.

Recombinant vaccinia virus and use thereof

The present invention relates to: a composition for alleviating or treating pain, the composition comprising glutamate decarboxylase and a gene coding for an anti-inflammatory cytokine; and a method for alleviating or treating pain by using the composition.

Composition for treating pain

Provided is a cell therapeutic agent for treating an inflammatory disease induced by a hyperimmune response, more specifically, a composition for treating an inflammatory disease induced by a hyperimmune response, which comprises (i) a chondrocyte or a cell capable of differentiating into a chondrocyte; and (ii) a cell into which a gene encoding TGF-&#x3b2; is introduced, wherein the cell in (ii) is derived from human embryonic kidney 293 (HEK-293) cell.

Composition for treating inflammatory disease induced by hyperimmune response

The present invention provides a poxvirus-derived promoter, a vector comprising the same, a method for expressing a transgene using the promoter, and use of the vector in the prevention or treatment of a disease. A promoter according to the present invention can be used for induction of strong expression of a transgene.

Poxvirus-derived promoter, and vector comprising same

A method for delivery of a therapeutic agent to a nervous tissue. In particular, a method of delivering a therapeutic agent to a nervous tissue protected by the brain-blood barrier or meninges is disclosed. The method for delivery allows delivery of a therapeutic agent to a nervous tissue with high efficiency. In addition, the delivery method of a therapeutic agent to a nervous tissue is safe since it has lower side effects such as nervous damage than a method of administering a therapeutic agent directly to a nervous tissue.

Method for delivery of biological molecule to nervous tissue

The present invention provides for a method of treating or preventing ischemic or liver disease in a subject by administering a composition reconstituted from a lyophilized hepatocyte growth factor (HGF) DNA formulation, where the DNA formulation comprises an HGF plasmid DNA, salt and a carbohydrate. The invention further provides for a method of making such a lyophilized DNA formulation that preserves or enhances gene expression both in vitro and in vivo, thus maintaining or stimulating the biological activity of the expressed protein. The invention also provides for the DNA formulation, or the lyophilized DNA formulation according to the methods disclosed.

Lyophilized DNA formulations for enhanced expression of plasmid DNA

The present invention relates to compositions and methods for fusion protein separation utilizing a peptide linker comprising a novel thrombin cleavage site.

Compositions and methods for fusion protein separation

The present invention relates to the use of internal promoters in mammalian expression vectors including plasmid vectors and enhancer-deleted retroviral vectors. The retroviral vectors have improved safety and optimal levels of transgene expression and vector titers.

Expression vectors with improved safety

Growing community of inventors

Seoul, South Korea

Sujeong Kim