Warner-lambert Company

Other

Mcneil-ppc, Inc.

Suhas H Ambike

Eric Blaser

Neema Kulkarni

Arthur P Wright

William Bess

Michael P Ramsay

Narinder S Grewal

Betty P Wen

Tai-Wing Ng

Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer, such as pullulan, and a taste masked pharmaceutically active agent, such as dextromethorphan. The taste masking agent is preferably a sulfonated polymer ion exchange resin comprising polystyrene cross-linked with divinylbenzene, such as AMBERLITE. Methods for producing the films are also disclosed.

Fast dissolving orally consumable films containing a taste masking agent

Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1

Continuous production of aluminum hydroxycarbonate gel by continuous reaction of aluminum salt solution with mixed alkaline carbonate and bicarbonate solution under homogeneous conditions in a relatively small reaction vessel, and continuing the reaction in a subsequent reaction vessel under controlled pH. The product gel is separated from the non-aluminum cation containing reaction mixture within less than about 6 hours, whereby formation of poorly soluble addition reaction products such as dihydroxy aluminium sodium carbonate, which contribute undesired non-aluminum cations to the gel product, is reduced. The aluminum salt solution is adjusted in pH by adding to it a portion of the mixed carbonate and bicarbonate solution to obtain a clear solution of pH 3.5 to 4.0. This results in a smooth, creamy gel with less objectionable chalky mouth feel.

Aluminum hydroxycarbonate gel

Dental hygiene compositions containing as antiplaque/antiseptic/deodorizing active ingredient highly pure alkali metal lauryl sulphate substantially free from non-lauryl alkyl salts.

Dental hygiene compositions

Aluminum hydroxycarbonate gel is precipitated under highly homogeneous conditions by continuously introducing an aluminum salt solution and an alkaline-reacting carbonate and bicarbonate solution into a vigorously agitated reactor vessel and continuously withdrawing the reaction mixture.

Preparation of aluminum hydroxycarbonate gels by a continuous process

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West Hill, Canada

Suhas H Ambike