Harvard College

Suhani D Vora

Alejandro Chavez

Benjamin W Pruitt

Jing Cheng

The present disclosure provides methods and compositions of modulating expression of a target nucleic acid sequence in a cell. The method comprises introducing into the cell a nucleic acid sequence encoding a Cas9 fusion protein and a guide RNA, wherein the Cas9 fusion protein and the guide RNA are expressed and co-localize at a target site and modulate the expression of the target nucleic acid sequence.

Growing community of inventors

Cambridge, MA, United States of America

Suhani D Vora