Toray Industries, Inc.

Suguru Ushiro

Yoshiyuki Ueno

Akihiro Hayashi

Hiroshi Takahashi

Tomonori Kawakami

Kaori Akaike

Takeshi Baba

Disclosed is a porous hollow fiber membrane containing a polysulfone-based polymer as a main component, which has an asymmetric structure in which the inner surface side is dense and the outer surface side is coarse, wherein an average of a minor axis diameter of pores of an inner surface is 20 nm or more and 40 nm or less, an open porosity of the inner surface is 10% or more and 30% or less, and a polymer including a monocarboxylic acid vinyl ester unit is supported on at least one of the outer surface and the inner surface. The present invention provides a hollow fiber membrane which has excellent removing performance of substances to be separated such as viruses, and can be used as a separation membrane having high permeability even in a treatment under low pressure.

Porous hollow fiber membrane

A copolymer is capable of being immobilized on a base material while maintaining a high antithrombotic property persistently without having to introduce heparin or an anticoagulant drug to the surface thereof. The copolymer includes monomer unit A, monomer unit B, and monomer unit C, wherein monomer unit C has a mole fraction of 0.5-40% with respect to the total amount of all constituent monomer units.

Copolymer and medical material containing the same

A biological component adhesion-suppressing material includes a substrate provided with a functional layer having, fixed on a surface thereof that comes into contact with a biological component, a polymer including a saturated aliphatic monocarboxylic acid vinyl ester unit, wherein: when compositional analysis is performed on the surface of the functional layer using a TOF-SIMS device, the number of carbon atoms in an aliphatic chain representing an ion signal detected for saturated aliphatic carboxylic acid is 2-20; and an XPS measurement taken of the surface of the functional layer shows a peak derived from an ester group.

Biological component adhesion-suppressing material

A medical material is capable of suppressing adhesion of platelets and proteins even when in contact with biological components such as blood for an extended period of time. The medical material is a copolymer including hydrophobic units and hydrophilic units in which the hydrophobic units have a C2-20 terminal alkyl group in a side chain, the static contact angle of water in the copolymer is at least 30&#xb0; and less than 70&#xb0;, and the glass transition temperature of the copolymer exists at only one point in the range from 45&#xb0; C. to less than 90&#xb0; C.

Medical material, medical separation membrane, and blood purifier

A copolymer has blood compatibility and antithrombotic properties of greatly suppressing protein adhesion to be usable even when in contact with a biological component such as blood for a long period of time, and a medical device uses the copolymer. The copolymer is characterized by including a hydrophilic unit and a hydrophobic unit, wherein the hydrophobic unit contains at least one type of a carboxylic acid vinyl unit, and the number of carbon atoms at the terminal of a side chain of the carboxylic acid vinyl unit is 2-7.

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Otsu, Japan

Suguru Ushiro