Otsuka Pharmaceutical Company, Limited

Lsi Medience Corporation

Mitsubishi Kagaku Latron, Inc.

Mitsubishi Chemical Medience Corporation

Suguru Akamatsu

Ayako Nishimura

Kiyonori Katsuragi

Toru Hadama

Mio Ooguchi

Hideaki Onishi

Midori Abe

Makoto Inada

Tokio Sawai

Tetsuya Tachikawa

Kazuki Tobita

Yoko Saijo

Jun-ichi Kunizaki

Shinji Iizuka

Jun-Ichi Kunizaki

A method is provided for measuring and evaluating rapidly and with high accuracy a subject's glucose metabolism. The method uses a labeled C-breath test and a composition that is suitably used in the method. The composition contains as active ingredient glucose labeled with at least one isotope of C, wherein the glucose is converted in the subject to labeled carbon dioxide that is excreted in expired air. This method also allows for the determination of a stage of a patient in whom diabetes has developed as well as for a stage before the onset of diabetes, and monitors the state (diabetes condition including a state before onset of diabetes) over time.

Method for measuring carbohydrate metabolism ability, and composition for use in said method

A monoclonal antibody that does not show a crossreactivity with middle-molecular weight (MMW) adiponectin and specifically reacts with high-molecular weight (HMW) adiponectin alone is disclosed. The monoclonal antibody of the present invention can be produced by using HMW adiponectin as an antigen. According to the monoclonal antibody of the present invention, a convenient, high-accurate, and versatile reagent for analyzing HMW adiponectin can be provided.

Monoclonal antibody for analyzing high-molecular weight adiponectin and utilization of same

To provide an immunological detection method which can detect or quantify a pneumococcal antigen in a sample derived from a living body conveniently, rapidly, and with high sensitivity, and an antibody for use in the method. The present invention provides an antibody which specifically recognizes a pneumococcal F-antigen; a method for detecting or quantitating a pneumococcal antigen, characterized in that the method detects or quantitates a pneumococcal F-antigen in a sample derived from a living body through immunological assay employing the antibody; and a kit for detecting a pneumococcal antigen, the kit containing the antibody.

Method for detection of pneumococcus

A latex reagent for analyzing adiponectin, comprising a suspension of latex particles carrying a substance which specifically binds to adiponectin, is disclosed. Further, a method for analyzing adiponectin, comprising (1) obtaining a biological liquid possibly containing adiponectin, and (2) bringing the biological liquid, while maintaining the state in which the biological liquid is obtained, into contact with a suspension of latex particles carrying a substance which specifically binds to adiponectin, and optically analyzing a degree of latex-particles-agglutination, is disclosed. According to the latex reagent and the method for analyzing adiponectin, a predilution or pretreatment of the biological liquid to be analyzed is not necessary. Further, the analysis can be performed rapidly and conveniently, and facilities therefor are not limited.

Latex reagent for adiponectin analysis and method of adiponectin analysis

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Osaka, Japan

Suguru Akamatsu