Olympus Optical Company, Ltd.

Sugio Manabe

Masahiko Sakurada

Taiichi Banno

Ryoichi Orimo

Kevin Galle

Nagahiro Gocho

Hideaki Okamura

Tauneaki Kadogaki

An automatic analyzing apparatus of this invention has first and second reaction container holders, a photometric unit, and a control unit. Each of the first and second reaction container holders is movable along a reaction line and has a plurality of reaction containers to which a liquid sample such as blood or urine can be injected. The photometric unit has a function of optically analyzing a concentration of a chemical component of the liquid sample injected in the reaction containers of the first and second reaction container holders when the first and second reaction container holders pass through it. A control unit has a function of stopping only either one of the first and second reaction container holders on the reaction line and moving the other reaction container holder along the reaction line to pass through the photometric unit.

Automatic analyzing apparatus and automatic analyzing method

A multi-item automatic chemical analyzer comprising a reagent delivery system for delivering a plurality of reagents of different kinds into reaction vessels in succesion is disclosed. The influence of contamination between the reagents upon measurement is reduced or eliminated by controlling the reagent delivery system with a control system comprising a memory unit for storing information representing a relation of the test items, particularly the influence of contamination between the reagents upon the measurement, and a center process unit for controlling the operation of reagent delivery system in accordance with the stored information.

Method for controlling reagent delivery system in automatic chemical

A photoelectric measuring apparatus for use in an automatic chemical analyzer in which a plurality of test items are analyzed by using light beams having different wavelengths, including a white light source for emitting a polychromatic light beam, a grating for diffracting the polychromatic light beam into a plurality of light beams having predetermined different wavelengths, a plurality of light guides for guiding the light beams emanating from the grating to a plurality of cuvettes containing test liquids to be analyzed, a plurality of light receiving elements for receiving light beams transmitted through the cuvettes, an additional light guide for guiding a polychromatic light beam emanating from the grating as the zero order light beam to a cuvette via an optical filter having a desired transmission wavelength, and an additional light receiving element for receiving a light beam transmitted through the cuvette.

Photoelectric measuring apparatus for use in automatic analyzer

An automatic analyzing apparatus for effecting chemical analyses for various sample liquids such as blood, urine, and the like, comprising a sample delivery pump for metering a sample liquid into a reaction cuvette, a reagent delivery pump for delivering to the reaction cuvette a given amount of a given reagent selected from a plurality of reagents contained in a reagent cassette, to form a test liquid, a feed mechanism for successively supplying reaction cuvettes along a circular reaction line, a plurality of photometering sections arranged along the reaction line for effecting a plurality of photometric and/or nephelometric and/or fluorometric measurements for each test liquid at different time instances to produce a plurality of photometric results, and circuitry for receiving the photometric results and selecting therefrom given quantitative analytical data of a given test item.

Automatic analyzing apparatus

An automatic analyzing apparatus for automatically effecting chemical analysis on a sample of blood, urea or the like dependent on measurement items by measuring the light absorption degree of a reaction liquid through a reaction vessel, comprising a reaction liquid photometric unit, a photometric unit independent of the reaction light photometric unit and operative to measure beforehand the light absorption degree of the reaction vessel per se or the reaction vessel containing a reagent or dilute liquid, and means for correcting the light absorption degree of the reaction liquid measured at the reaction liquid photometric unit on the basis of the light absorption degree of the reaction vessel per se or the light absorption degree of the reaction vessel containing the reagent or dilute liquid measured at the independent photometric unit.

A turntable is arranged rotatably in both directions and a plurality of reaction vessels are arranged along a periphery of the turntable. Along the circumference of turntable are arranged a reagent delivery unit for delivering a given amount of reagent into successive reaction vessels, a sample delivery unit for delivering a given amount of samples into successive reaction vessels and a plurality of photometering units for measuring an absorbance of a test liquid contained in each reaction vessel. The turntable is first rotated in a backward direction by four steps and then is rotated in a forward direction by five steps, so that the turntable is advanced in the forward direction by one step at the end of the forward movement. Between successive backward and forward movements the test liquid is measured at a first time by the photometry unit and between successive forward and backward movements the same test liquid is measured at a second time by the same photometry unit and in this manner successive test liquids are measured twice by each of the photometry units. An analytical result can be obtained by processing all the measured values supplied from all the photometry units.

Chemical analyzing apparatus

In a method of analyzing chemical substances in sample liquids, reagent blank absorbances with respect to a light amount transmitted through air or water are measured previously at a plurality of photometering positions and are stored in a memory. Then sample absorbances are measured at respective photometering positions and the reagent blank absorbances are substrated from the sample absorbances at the respective photometering positions, so that a required absorbance variation of the sample liquid with respect to time is calculated from the sample absorbances thus corrected. Therefore, even if a calibration curve linearity is not perfectly identical with each other at the respective photometering positions, it is possible to obtain accurate analyzing results.

Method of analyzing chemical substances

A method of enhancing the accuracy and reliability of a chemical analysis, wherein a reaction is carried out by combining a sample liquid with at least one reagent to form a test liquid and the test liquid is photometrically scrutinized a plurality of times over an extended period of time to derive a number of photometric values. The derived values are then stored and a plurality of the stored photometric values are preliminarily selected from a given time frame, wherein the plurality of preliminarily selected values are less than a total number of stored photometric values. Successive preliminarily selected photometric values are compared with at least one predetermined standard to derive a comparison result and upon indication that useful data cannot be calculated from the preliminarily selected photometric values, a secondarily selecting step of selecting at least one photometric value from all of the stored photometric values, which were not preliminarily selected, is used to derive an analytical result which represents a concentration of a chemical substance in the test liquid or an activity of the test liquid.

An automatic chemical analyzing apparatus comprising means for feeding successive reaction vessels along a circular reaction line, a sample delivery pump for delivering a given amount of sample liquids to be tested into the reaction vessels, a reagent delivery pump for delivering a given amount of reagent (corresponding to a particular test item to be measured) selected from a plurality of reagents, a first photometering means provided along the circular reaction line for monitoring the reaction condition of a test liquid in the reaction vessel on the reaction line, a second photometering means arranged in a precise photometering section positioned underneath the reaction line, means for transporting the reaction vessel from the reaction line into the precise photometering section after the test liquid in the relevant vessel has been monitored to reach a given reaction condition.

An automatic analytical apparatus for effecting quantitative analysis of a given substance contained in a sample such as blood, urine or the like and comprising a sample holding and carrying means including a plurality of sample holding positions and operative to carry the sample held by one of the sample holding positions more than one round along a closed loop, a photometric means fitted to a given position of the closed loop and operative to effect at least two photometric operations, a transfer means for transferring one sample to the sample holding position without transferring any other sample to the latter, and a discarding means operative to discard the sample only which has been subjected to the given number of photometric operations.

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Kodaira, Japan

Sugio Manabe