Bigtec Private Limited

Centre for Cellular and Molecular Platforms (c-camp)

Indian Institute of Technology Madras

Centre for Cellular and Molecular Platforms

Sudip Mondal

Chandrasekhar Bhaskaran Nair

Pillarisetti Venkata Subbarao

Sathyadeep Viswanathan

Renjith Mahiladevi Radhakrishnan

Raviprakash Jayaraman

Kishore Krishna Kumar

Taslimarif Saiyed

Sankaranand Kaipa Narasimha

Manjula Jagannath

Shilpa Chennakrishnaiah

Swetha Chandra

Venkataraman Venkatakrishnan

Venkatakrishnan Venkataraman

Anil Prabhakar

H Krishnamurthy

The present disclosure provides a non-contact real time micro Polymerase Chain Reaction (PCR) system comprising; a chip having a reaction chamber for holding a sample and an embedded metal heater below the reaction chamber for heating the sample; an optical unit comprising an associated LED driver and a photo detector amplifier placed above the chip to detect fluorescence; an induction heater mounted around the chip and inductively coupled to the metal heater; an infrared temperature sensor mounted below the chip for measuring a temperature of the metal heater, wherein the infrared temperature sensor is interfaced with a signal conditioner; and a controller interfaced with the signal conditioner and the induction heater for regulating the power to the induction heater based on feedback received from the infrared temperature sensor through the signal conditioner.

Non contact real time micro polymerase chain reaction system and method thereof

Instant invention is about a hand held micro PCR device comprising a LTCC micro PCR chip comprising a heater, a reaction chamber to load a sample. It also comprises a heater control to regulate the heater on basis of input received from a temperature sensor. It further has an optical system having an optical fiber to detect a fluorescence signal from the sample, and at least one communication interface to interact with other device(s).

Hand held micro PCR device including microcontroller for exchanging information with a communications interface

The present disclosure is related to a microfluidic flow analyzer for pathological detection. The microfluidic flow analyzer comprises plurality of buffer channels, sample channel, central flow channel, plurality of exciting optical channels and plurality of receiving optical channels. The plurality of exciting optical channels and the plurality of receiving optical channels are placed at predetermined angle to the central flow channel. The plurality of exciting optical channels excite cell in the sample solution flowing through the central flow channel. The cell being excited produces one or more optical signals. The one or more optical signals are received by the plurality of receiving optical channels. The microfluidic flow analyzer comprises plurality of detectors placed on each of the plurality of receiving optical channels for detecting one of the one or more optical signals. The detected optical signal is sent to a computing unit for pathological detection.

Microfluidic-based flow analyzer

Growing community of inventors

Bengaluru, India

Sudip Mondal