Ptt Global Chemical Public Company Limited

Myriant Corporation

Sudhanshu Vijay Dole

R Rogers Yocum

Janice G Pero

Theron Hermann

Wei Gong

Russell Lizardo Udani

Tammy Grabar

Andrew Christopher Collard

Mark Andrew Sheff

Sean Joseph Regan

Yeast strains and fermentation process for producing D-lactic acid and L-lactic acid are disclosed with higher titer, higher yield, shorter time, lower pH, and higher average specific productivity.

Microorganisms and processes for lactic acid production

This invention relates to the biosynthesis of organic acids in genetically modified microorganisms. More specifically, this invention provides genetically modified microorganisms that are particularly tolerant to organic acids at low pH and are capable of producing organic acids by fermentation at low pH.

Production of organic acids by fermentation of genetically engineered yeast cells at low pH

This present invention relates to production of chemicals from microorganisms that have been genetically engineered and metabolically evolved. Improvements in chemical production have been established, and particular mutations that lead to those improvements have been identified. Specific examples are given in the identification of mutations that occurred during the metabolic evolution of a bacterial strain genetically engineered to produce succinic acid. This present invention also provides a method for evaluating the industrial applicability of mutations that were selected during the metabolic evolution for increased succinic acid production. This present invention further provides microorganisms engineered to have mutations that are selected during metabolic evolution and contribute to improved production of succinic acid, other organic acids and other chemicals of commercial interest.

Engineering microbes for efficient production of chemicals

This invention relates to succinic acid production from renewable feedstock using microbial biocatalysts genetically modified to produce succinic acid in commercially significant quantities. More specifically, this invention relates to the genetic manipulations in the pathway of carbon from renewable feedstock to succinic acid.

Organic acid production in microorganisms by combined reductive and oxidative tricaboxylic acid cylce pathways

Growing community of inventors

Andover, MA, United States of America

Sudhanshu Vijay Dole