William Robert Arathoon Living Trust Dated August 29, 2016

Suchismita Mohanty

Qianting Zhai

Raffaella Briante

Cindy Tan

Paul David Ponath

Evan Matthew Bishop

William Robert Arathoon

Alissa Loren Briggs

Provided are multi-specific antibodies that target both a cellular efflux pump and a cancer-associated antigen as well as pharmaceutical compositions, nucleic acids, recombinant expression vectors, cells, and kits that include or encode such multi-specific antibodies. Methods of treating a subject for a cancer that include administering to the subject a multi-specific antibody that targets both a cellular efflux pump and a cancer-associated antigen are also provided. Provided as well are methods of generating the described multi-specific antibodies and reagents related thereto, including genetically modified cell lines useful in the subject methods and methods of making such genetically modified cell lines.

Efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto

Growing community of inventors

Millbrae, CA, United States of America

Suchismita Mohanty