Council of Scientific and Industrial Research

Other

Subhash Chandra Gupta

Suman Preet Singh Khanuja

Ajit Kumar Shasany

Mahendra Pandurang Darokar

Madan Mohan Gupta

Vivek Kumar Gupta

Monika Singh

Sushil Kumar

Jai Shankar Arya

Prachi Sinha

Soumya Awasthi

Sunil Balkrishna Mansinghka

Suresh Haribhau Dawle

Sweta Agarwal

Ram Kishore Verma

Dharmendra Saikia

Anirban Pal

Anil Kumar Singh

Ravi Prakash Bansal

Santosh Kumar Srivastava

Arun Kumar Tripathy

Subash Chandra Verma

Pushplata Chaturvedi

Krishna Kumar Aggarwal

Ranganathan Santha Kumar Tiruppadiripuliyur

Harpreet Kaur

Jai Shanker Arya

Vinay Kumar Agarwal

The present invention provides an improved preparation based on the synergistic action of garlic extract and essential oil ofvar. Ganga or cinnamon oil against dermatophytic fungus. More particularly, the present invention relates to the synergistic enhancement of activity of a combination by menthyl acetate or Geraniol. The invention also provides a method of preparation of the synergistic combination and the shelf life observed to be more than one year. The cream based preparation is a potent anti-dermatophytic as described and illustrated by in vitro and in vivo evaluations.

Anti-dermatophytic preparation and use thereof

The invention relates to a novel pharmaceutical composition comprising an effective amount of bio-active fraction from cow urine distillate as a bioavailability facilitator and pharmaceutically acceptable additives selected from anticancer compounds, antibiotics, drugs, therapeutic and nutraceutic agents, ions and similar molecules which are targeted to the living systems.

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Use of bioactive fraction from cow urine distillate ('go-mutra') as a bio-enhancer of anti-infective, anti-cancer agents and nutrients

The present invention relates to a novel nitrile glycoside of Formula I named NIAZIRIDIN and to analogues and derivatives thereof. The present invention also relates to a process for the isolation of a novel nitrile glycoside of Formula I below named NIAZIRIDIN and its derivatives and analogues by bioactivity-guided fractionation from the pods ofThe present invention particularly relates to the bioenhancing activity of the novel nitrile glycoside of Formula I below named NIAZIRIDIN and its derivatives and analogues in enhancing bioactivity of commonly used antibiotics such as rifampicin, tetracycline and ampicillin against Gram (+) and (&#x2212;) bacteria. The biomolecule also enhances the absorption of drugs, vitamins and nutrients through the gastro-intestinal membrane increasing their bio-availability. Therefore niaziridin can be used in combination therapy with drugs and nutrients resulting in reduced drug associated toxicity, reduced cost and duration of chemotherapy.

Nitrile glycoside useful as a bioenhancer of drugs and nutrients, process of its isolation from moringa oleifera

A pharmaceutical composition comprising an antibiotic and cow urine distillate in an amount effective to enhance antimicrobial effect of the antibiotic is disclosed. The antibiotic can be an antifungal agent. The antibiotic can be a quinolone or a fluoroquinolone. The antifungal agent can be azoles, clotrimazole, mystatin or amphotericin.

Pharmaceutical composition containing cow urine distillate and an antibiotic

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Lucknow, India

Subhash Chandra Gupta