Sami Labs Limited

Other

Sabinsa Corporation

Majeed, Muhammed

Kumar, Arvind

Prakash, Subbalakshmi

Nagabhushanam, Kalyanam

Badmaev, Vladimir

Bammi, Rajinder Kumar

Subbalakshmi Prakash

Muhammed Majeed

Kalyanam Nagabhushanam

Rajinder Kumar Bammi

Vladimir Badmaev

Rajendran Ramanujam

Samuel Manoharan Thomas

Rattan Sood

Renukeshwar H Chandramouli

Susmitha Anand

Nagabhushanam Kalyanam

Sankaran Natarajan

Natarajan Sankaran

Savita Ganjihal

Geetha Kanhangad-Gangadharan

Nagarajan Ananthanarayanan

Arvind Kumar

Kalyanam Nagabushnam

Seena George

Ramanujam Rajendran

Venu Agarwal

Shipra Roy

Tirumale Sharmila

KanhangadGangadharan Geetha

KalkunteSeshadri Satyan

Sivaprakash Kurumanghat Balakrishnan

Kalyanam Nagebhuananam

Sivaprskash Kurumanghat Balakrishnan

Susmitha Anand Tathapudi

The present invention relates to a composition containing peptide of SEQ ID NO: 1 linked to oleanolic acid and a method of treating skin aging. The composition effectively reduces signs of ageing due to oxidation, collagen insufficiency and excess activity of serine proteases like elastase and collagenase that result in wrinkling of skin, fine expression lines, reduced skin thickness, hyperpigmentation, under eye dark circles, and premature ageing.

Oleanoyl peptide composition and method of treating skin aging

Optimal compositions of derivatives of 5-methyl-3(2H)-furanone compounds and phenylpropanoid polyketides related to inotilone, that exert biological response modification in health and disease, and their method of preparation, are disclosed. Methods of treating degenerative conditions stemming from over-expression of inducible nitric oxide synthase (iNOS) using these compositions are also disclosed.

Inotilone derivatives as coherent biological response modifier (cBMR)

The present invention relates to the Synthesis of Triterpenoid peptides and mechanism of action for Anti ageing and skin care. The present invention is directed towards anti-aging skin care compositions comprising peptides which are made by linking herbal actives to a pentapeptide for enhanced anti ageing activity by regenerating the dermal matrix. In detail, the present invention relates to the synthesis of Triterpenoid peptides, providing an enhanced and synergistic activity for reducing the consequences of ageing such as appearance of fine expression lines and wrinkles on the skin by cosmetic modes of application. The Triterpenoid peptides of the present invention with its novel dual action mode can be used for skin ageing & collagen insufficiency. Its Triterpenoid group acts by preventing oxidation and excess activity of serine proteases like elastase and collagenase that result in wrinkling of skin. With added peptides which boost the collagen and other matrix protein, Triterpenoid peptides provide a complete protection against pre mature ageing and functions as a best anti ageing ingredient.

Peptides modified with triterpenoids and small organic molecules: synthesis and use in cosmeceuticals

The invention describes compositions and methods for the management of hyperproliferative skin conditions such as psoriasis. The preferential composition contains a natural leukotriene inhibitor selected fromgum resin, its extractives, isolates or derivatives in combination with a bioavailable organic selenium nutritional supplement. These compositions are administered orally and topically to the individual human or animal in need of treatment at optimal levels to manifest the desired benefits, with no untoward side effects

Compositions and methods for the management of hyperproliferative dermatological conditions

Disclosed are novel, synthetic analogues of (1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione and the therapeutic applications for cystic fibrosis thereof in correcting altered CFTR trafficking and the associated impaired chloride (Cl) ion transport. Introduction of branched-alkyl groups ortho to the phenolic groups gave rise to clinical compounds with vastly improved trafficking of delF508CFTR and with no cytotoxicity.

Non-cytotoxic synthetic analogues of (1E, 6E)-1, 7-Bis (4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-Dione and therapeutic applications thereof in cystic fibrosis

A novel process for the synthesis of (S)-3-Amino-tetrahydrofuran and (R)-3-Amino-tetrahydrofuran is described. The process is applicable for substituted chiral-3-aminotetrahydrofuran derivatives.

Processes for the manufacture of chiral and racemic forms of 3-aminotetrahydrofurans, their salts and derivatives

The invention relates to methods of treatment and pharmaceutical compositions of new chemical compounds that inhibit the various enzymes in the arachidonic acid pathway implicated in inflammatory disease conditions.

Chemical entities with multiple modes of anti-inflammatory action

The invention relates to new chemical compounds that inhibit the various enzymes in the arachidonic acid pathway implicated in inflammatory disease conditions.

Alkoxy aromatic compounds are conveniently dealkylated to the corresponding phenolic compounds by treatment with aluminum chloride/N,N-dimethyl aniline complex. Aromatic poly O-demethylation is a unique feature of this invention. This process is applicable to the manufacture of polyphenols such as Resveratrol, Oxyresveratrol, Gnetol.

Process for the synthesis of biologically active oxygenated compounds by dealkylation of the corresponding alkylethers

The present invention discloses an economically viable process for producing large quantity of higher fatty alcohol of chain length C&#x2013;Cfrom natural waxes. The said alkanols have enriched percentage of 70&#x2013;95% of Cfatty alcohol (Octacosanol) along with less percentage of lower chain length fatty alcohols. The invention discloses the use of supercritical carbon dioxide extraction along with immobilized enzyme for saponification. The present invention also discloses the cosmetic applications of alkyalkanols collectively referred to as policosanol, for control of sebum secretion and as anti-acne component effectively used in cosmetic formulations.

[object Object]

The invention describes compositions and methods containing nonconventional plant materials, and more particularly the speciesand, that help to maintain normal blood sugar levels in humans and animals. The method of preparation of such compositions and methods of quantifying active principles therein are also described. A Metformin-like compound were found to be the active hypoglycemic principle inandroot bark. The compositions of the invention were found to be safe for therapeutic use.

Compositions and methods containing natural compounds from nonconventional sources that are useful in maintaining normal blood sugar levels

The invention discloses a method to prepare concentrates fromLinn. (Garlic) bulbs naturally enriched with an unique composition of organic selenium compounds and the use of such concentrates in nutritional supplement compositions for human and animal use. The resulting compositions provide a safe and efficacious means of providing supplemental amounts of the essential trace mineral nutrient selenium for diverse health benefits.

The invention discloses compositions containing Se-methyl-L-selenocysteine with enhanced bioavailability and superior antioxidant and immunomodulatory activity. These compositions can be used for nutritional supplementation in humans and animals.

Compositions and methods containing bioavailable Se-methyl-L-selenocysteine for human and veterinary use

Aqueous solutions of diterpenes such as Forskolin, its congeners, analogs and derivatives, up to approximately 6% concentration, are prepared using suitably substituted cyclodextrin as a solubilizing agents. In the absence of cyclodextrin, some diterpenes such as Forskolin are soluble in water only to concentrations of about 0.001%. Such aqueous solutions find applications in topical and systemic use, as pharmaceutical, cosmeceutical, nutraceutical preparations containing diterpenes such as Forskolin and congeners.

Process for preparing water soluble diterpenes and their applications

Tetrahydropiperine and analogs and derivatives thereof, including dihydropiperine, are disclosed to enhance the absorption and/or bioavailablity of nutrients, drugs and other organic compounds, such as insectides.

Growing community of inventors

Piscataway, NJ, United States of America

Subbalakshmi Prakash