Samsung Electronics Co., Ltd.

Lg Electronics Inc.

Snu Rdb Foundation

Su-hyeon Kim

Jeong-gun Lee

Kak Namkoong

Chin-sung Park

Jin-tae Kim

Young-Sun Lee

Hye-Jung Cho

Yoon-kyoung Cho

Byung-chul Kim

Beom-seok Lee

Nam Huh

Jun-Hong Min

Tae-Jin Ahn

In-seok Kang

In-ho Lee

Kui-hyun Kim

Jong-suk Chung

June-young Lee

Jeo-young Shim

Jin-Tae Kim

Sung-young Lee

Sang-eun Lee

Seong-ho Cho

Tae-Han Kim

Kyu-sang Lee

Kyu-tae Yoo

Kwang-wook Oh

Kyoung-Gu Woo

Sung-ouk Jung

SoYeon Ahn

Taesung Park

Kwang-ho Cheong

Hee-jeong Jeong

Je-Kyun Park

Gyeong-sik Ok

Joon-shik Park

Young-ho Park

Kyu-Sik Yun

Jeong-Gun Lee

Jo-Kyun Park

Sung-ho Won

Seung-yeoun Lee

Bora Yeon

An efficient and accurate method of identifying a target biomolecule in a sample by using target molecule-probe binding frequencies is disclosed.

Method of identifying target biomolecule by using probe-binding frequency

A fluid reaction device includes a microfluidic reaction chip which accommodates a fluid, a heater, and a heat transfer facilitating layer which is interposed between the microfluidic reaction chip and the heater, the heat transfer facilitating layer has a higher thermal conductivity than air and can hold particles, wherein formation of an air layer can be prevented.

Method of reducing temperature difference between a pair of substrates and fluid reaction device using the same

Provided is a field effect transistor (FET) type biosensor including a source electrode, a gate, and a drain electrode. A ligand that can bind to a side of a nucleic acid is added to the surface of the gate. In a conventional FET type biosensor, it is difficult to detect a signal within the debye length because a target nucleic acid is directly fixed to the surface of a gate of the conventional FET. However, in the present invention, this problem can be overcome and the debye length can be increased by treating the surface of a gate of an FET sensor with a ligand that can bind to a side of a nucleic acid. The ligand can be adsorbed onto the surface of the gate. In this case, the nucleic acid is adsorbed parallel to the surface of the gate, not perpendicular to the surface of the gate, thus generating an effective depletion region. In addition, hybridization efficiency can be increased because a hybridized sample can be injected into an FET sensor at high ionic strength.

FET-type biosensor with surface modification

A nano particle tracking device includes a channel structure. The channel structure of the nano particle tracking device includes a pair of microchannels in which a specimen including nano particles is accommodated and which face each other, at least one nano channel which is between the pair of microchannels, which connects the pair of microchannels to each other and through which the nano particles in the specimen are moved, and a nano grating below the nano channel and crossing the nano channel perpendicularly.

Nano particle tracking device, channel structure of the nano particle tracking device, and method of fabricating the channel structure of the nano particle tracking device

A bio material receiving device includes a thin film transistor ('TFT') including a drain electrode, and a nano well accommodating a bio material. The drain electrode includes the nano well. The TFT may be a bottom gate TFT or a top gate TFT. A nano well array may include a plurality of bio material receiving devices. In a method of operating the bio material receiving device, each of the bio material receiving devices may be individually selected in the nano well array. When the bio material is accommodated in the selected bio material receiving device, a voltage is applied so that another bio material is not accommodated.

Bio material receiving device and methods of manufacturing and operating the same

A method of recovering a nucleic acid sequence using a probe map includes: aligning a probe onto a target sequence based on a result in which the probe is hybridized to the target sequence; determining a representative value representing each aligned position of the probe; and recovering a base sequence of the target sequence by using a probe map to which the determined representative values and base sequence information of the probe are mapped.

Method and apparatus for recovering gene sequence using probe map

Provided are an automatic analyzing method and apparatus for a microfludic system. The apparatus includes means for recognizing a disc or chip in the microfludic system, performs an operation and detection by automatically loading a DB according to a recognized type, and perform quantization of a test.

Automatic analyzing method and apparatus for microfluidic system

An apparatus for printing a biomolecular droplet onto a substrate using an electric charge concentration effect includes; an electric field forming electrode including an accommodating area in which the biomolecular droplet including micro magnetic beads is accommodated and a nozzle formed on an end of the accommodating area through which the biomolecular droplet is discharged, a substrate disposed below the electric field forming electrode, including a grounded target surface onto which the biomolecular droplet discharged from the nozzle of the electric field forming electrode is deposited, a magnet disposed below the substrate which applies a magnetic force on the micro magnetic beads, and an open circuit type voltage applying unit electrically connected to the electric field forming electrode which applies a charge to the electric field forming electrode which generates an electrical force which causes the biomolecular droplet to be ejected onto the target surface of the substrate.

Apparatus and method for printing biomolecular droplet on substrate

Provided are magnetic particles for nucleic acid sequencing and a method of sequencing nucleic acid using the same. The nucleotide sequence of a target nucleic acid may be efficiently determined using the magnetic particles and the method of sequencing nucleic acid using the same.

Magnetic particles for nucleic acid sequencing and method of sequencing nucleic acid using the same

An apparatus separating a polarizable analyte using dielectrophoresis includes a vessel including a membrane having a plurality of nano- to micro-sized pores, the membrane disposed inside the vessel, electrodes generating spatially non-uniform electric fields in the nano- to micro-sized pores of the membrane when an AC voltage is applied to the electrodes, and a power source applying the AC voltage to the electrodes, wherein a sectional area of the pores varies along a depth of the pores. A method of separating a polarizable material uses the apparatus.

Apparatus for and method of separating polarizable analyte using dielectrophoresis

A multi-channel fluorescence measuring optical system and a multi-channel fluorescence sample analyzer using the optical system are provided. The multi-channel fluorescence measuring optical system, which irradiates light onto a plurality of sample channels and detecting fluorescence radiated from samples, includes: a light source; an integrator for giving the light irradiated from the light source a uniform intensity distribution; a sample holder having a plurality of sample channels on which the samples are mounted, wherein the samples are exited by the light emitted from the integrator; and a beam splitter between the integrator and the sample holder for dividing the incident light in a predetermined ratio. Since the light intensities of fluorescence images are detected using optical fiber bundles and photodiodes, the manufacturing cost can be greatly reduced, and the optical system can be miniaturized.

Multi-channel fluorescence measuring optical system and multi-channel fluorescence sample analyzer

A cell lysis device for lysing cells or viruses, comprising a cell lysis tube having a sample inlet; a pump connected to the cell lysis tube for transferring a sample into the tube; a sealing unit for reversibly sealing a specific region of the tube; and a laser source for generating a laser is provide. Further, a method of lysing cells or viruses using the cell lysis device is provide. The method comprises introducing a sample containing cells or viruses and optionally magnetic beads to the cell lysis tube through the sample inlet; transferring the sample to a specific region in the cell lysis tube by means of the pump; temporarily sealing the region of the cell lysis tube where the sample is placed with the sealing unit; irradiating the sample with the laser; removing the sealing unit from the cell lysis tube; and discharging the sample from the cell lysis tube by means of the pump.

Device and method for rapidly lysing cells or viruses

A device for printing a droplet onto a substrate includes: a droplet generating member which is needle-shaped and comprises a receiving portion disposed vertically to receive a solution, and a discharge hole connected to the receiving portion and formed on a bottom of the receiving portion so that the solution can be discharged from the receiving portion; a substrate disposed below the droplet generating member, the substrate includes a target portion to which the droplet discharged from the discharge hole of the droplet generating member is dropped and attached; a voltage applier applying a voltage to the droplet so that the droplet can be dropped onto the target portion of the substrate; a volume measuring unit measuring the volume of the droplet; and a droplet control unit maintaining the volume of the droplet at a predetermined level based on the measured volume of the droplet.

Device for printing droplet or ink on substrate or paper

A method of reducing a temperature difference between a high-temperature and a low-temperature substrate includes interposing a heat transfer facilitating layer which has a higher thermal conductivity than air and can hold particles between the substrates, and maintaining close contact between the high-temperature substrate, the heat transfer facilitating layer, and the low-temperature substrate, wherein formation of an air layer can be at least substantially prevented between the high-temperature substrate and the heat transfer facilitating layer, and between the low-temperature substrate and the heat transfer facilitating layer.

Method of reducing temperature difference between a pair of substrates

A micro-fluid reaction vessel includes an upper plate formed of an elastomer, a lower plate adhered to the upper plate, a micro-chamber and a micro-channel formed on an inner surface of the upper plate facing the lower plate and an inlet hole and an outlet hole formed in the upper plate and through which a fluid flows into or out of, respectively. The micro-channel is constructed to be closed by pressure applied to the upper plate and elastically restored when the pressure is not applied. A micro fluid reaction method uses the micro fluid reaction vessel and a method of manufacturing forms the microfluid reaction vessel.

Micro-fluid reaction vessel, method for manufacturing the same, and micro-fluid reaction method using the vessel

Growing community of inventors

Seoul, South Korea

Su-hyeon Kim