Spineovations, Inc.

Other

Sprezzatura Innovations, LLC

Stuart W Young

Neville Alleyne

Nicholas J Manesis

Jonathan L Sessler

Tarak D Mody

Darren Magda

Meredith Wright

Nevile Alleyne

Nicholas John Manesis

A method of treating a spinal disk according to the present invention can include inserting an alloplastic bulking agent into the spinal disk to treat the defect. The alloplastic bulking agent has a plurality of microparticles and a suspending agent comprising hyaluronic acid. The bulking agent results in at least one of sealing the defect, increasing a pressure of the disk, increasing a height of the disk, improving stability of the disk and improving structural integrity of the disk.

Method of treating spinal disk

A method of treating a spinal disk according to the present invention can include inserting an alloplastic bulking agent into the spinal disk to treat the defect. The alloplastic bulking agent has a plurality of microparticles. The bulking agent results in at least one of sealing the defect, increasing a pressure of the disk, increasing a height of the disk, improving stability of the disk and improving structural integrity of the disk.

Method of treating spinal internal disk derangement

The present technology relates to methods and devices for augmenting the canine coxofemoral joint. In particular, methods for augmenting the capsule of the canine coxofemoral joint are provided. In some embodiments, augmentation can be performed by injecting an implantable device comprising a biodegradable matrix and microparticles into the capsule. In some embodiments, augmentation can be performed by imbricating an implantable device comprising a biodegradable matrix and microparticles at the capsule.

Methods and compositions for minimally invasive capsular augmentation of canine coxofemoral joints

A method of treating a ligament or tendon according to the present invention can include inserting a tissue-generating implant into the ligament or tendon to thereby treat the defect. The tissue-generating implant has a plurality of microparticles. The microparticles subsequently form a biological scaffold which operates at least as partial connective tissue in the ligament or tendon giving structural support during regrowth.

Method of using an implant for treament of ligaments and tendons

Compositions having a texaphyrin-lipophilic molecule conjugate loaded into a biological vesicle and methods for imaging, diagnosis and treatment using the loaded vesicle are provided. For example, liposomes or red blood cells loaded with a paramagnetic texaphyrin-lipophilic molecule conjugate have utility as a blood pool contrast agent, facilitating the enhancement of normal tissues, magnetic resonance angiography, and marking areas of damaged endothelium by their egress through fenestrations or damaged portions of the blood vascular system. Liposomes or cells loaded with a photosensitive texaphyrin-lipophilic molecule conjugate can be photolysed, allowing for a photodynamic therapy effect at the site of lysis. Availability of red blood cells loaded with a photosensitive texaphyrin-lipophilic molecule conjugate provides a method for delivering a photodynamic therapeutic agent to a desired site with a high concentration of oxygen. By presenting the agent in this way, it is expected that a patient will experience less toxicity.

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Portola, CA, United States of America

Stuart W Young