Genentech, Inc.

The General Hospital Corporation

Stuart Bunting

Hanspeter Gerber

Xiao Huan Liang

Ross G Clark

Ralph H Schwall

Hans-Peter Gerber

Hongkui Jin

Renhui Yang

Herman K Gold

Robert C Leinbach

Nancy Gillett

ANGPTL4 compositions and methods of using such compositions, and agonists or antagonists thereof, for the diagnosis and treatment of diseases or disorders are included, including methods to modulate cell proliferation, cell adhesion, and cell migration.

Methods of using angiopoietin-like 4 protein to stimulate proliferation of pre-adipocytes

Compositions and methods of using angiopoietin-like 4 protein antibody

Methods for treating vascular stenosis using hepatocyte growth factor ('HGF') are provided. In the methods, HGF can be administered to enhance re-surfacing of blood vessels damaged or traumatized, for instance, by vascular surgery or angioplasty. Articles of manufacture and kits containing HGF are also provided.

Methods and compositions for treating vascular stenosis

A mammal with congestive heart failure is treated by administering to the mammal an effective amount of growth hormone. Treatment results in increased left ventricular cystolic pressure, increased left ventricular maximum, increased cardiac output, and increased stroke volume index. Treatment also results in reduced left ventricular end-diastolic pressure and reduced systemic vascular resistance. These measurements indicate improvement in cardiac function by increased ventricular contractility and decreased peripheral vascular resistance.

Treatment of congestive heart failure

Growing community of inventors

Montara, CA, United States of America

Stuart Bunting