Axxia Technologies

Johns Hopkins University

Axxia Pharmaceuticals, LLC

Stuart A Grossman

Kam W Leong

Raghu Raghavan

Wayne C Pollock

Hungnan Lo

Robert Hobbs

Katherine Hartman

Glenn J Lesser

Susannah Ellsworth

Eric Ford

Lawrence Kleinberg

The present invention discloses systems and methods for calculating the radiation doses received by circulating blood cells. The present method may be applicable for calculating the radiation doses by circulating blood cells through any site in a patient. The present invention also discloses computer systems for calculating radiation doses received by circulating blood cells in a patient.

System and method for determining radiation dose to circulating blood

Methods and systems for providing planning and dispensation of research and/or treatment for brain disease. Radiological information is generated in a region of interest in an area of the a brain of an individual using a radiological imaging system. A physiological states model is constructed which assesses physiological states of the region of interest. Locations of sources of interstitial fluid flow, fluid conductivities of paths, and anatomical information in the region of interest are obtained using the radiological imaging information. Velocities of the interstitial fluid flow in the region of interest are computed using the physiological states model, the locations of sources of interstitial flow, the fluid conductivities, and the anatomic information. A model of the area of the brain is created, the model including the region of interest.

Methods and systems for providing planning and dispensation of research and/or treatment for brain disease

A non-abusable, non-inflammatory, biocompatible, non-biodegradable, subcutaneous, polymeric implant for the prolonged, controlled release of hydromorphone with near zero-order kinetics is described. Methods of alleviating cancer pain and treating opioid drug addiction with the implant are also described.

Subcutaneous implant

Subcutaneous implant for delivery of hydromorphone

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Towson, MD, United States of America

Stuart A Grossman