Koninklijke Philips Corporation N.v.

Stojan Trajanovski

Dimitrios Mavroeidis

Gary Nelson Garcia Molina

Adrienne Heinrich

Sander Theodoor Pastoor

Bart Jacob Bakker

Binyam Gebrekidan Gebre

Tsvetomira Kirova Tsoneva

Antonio Aquino

Birpal Singh Sachdev

Jesse Salazar

Ulf Grossekathöfer

Dimitros Mavrieudus

Typically, high NREM stage N3 sleep detection accuracy is achieved using a frontal electrode referenced to an electrode at a distant location on the head (e.g., the mastoid, or the earlobe). For comfort and design considerations it is more convenient to have active and reference electrodes closely positioned on the frontal region of the head. This configuration, however, significantly attenuates the signal, which degrades sleep stage detection (e.g., N3) performance. The present disclosure describes a deep neural network (DNN) based solution developed to detect sleep using frontal electrodes only. N3 detection is enhanced through post-processing of the soft DNN outputs. Detection of slow-waves and sleep micro-arousals is accomplished using frequency domain thresholds. Volume modulation uses a high-frequency/low-frequency spectral ratio extracted from the frontal signal.

Enhancing deep sleep based on information from frontal brain activity monitoring sensors

A concept for training a neural network model. The concept comprises receiving training data and test data, each comprising a set of annotated images. A neural network model is trained using the training data with an initial regularization parameter. Loss functions of the neural network for both the training data and the test data are used to modify the regularization parameter, and the neural network model is retrained using the modified regularization parameter. This process is iteratively repeated until the loss functions both converge. A system, method and a computer program product embodying this concept are disclosed.

Training a neural network model

Presented are concepts for feature identification in medical imaging of a subject. One such concept processes a medical image with a Bayesian deep learning network to determine a first image feature of interest and an associated uncertainty value, the first image feature being located in a first sub-region of the image. It also processes the medical image with a generative adversarial network to determine a second image feature of interest within the first sub-region of the image and an associated uncertainty value. Based on the first and second image features and their associated uncertainty values, the first sub-region of the image is classified.

Feature identification in medical imaging

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Eindhoven, Netherlands

Stojan Trajanovski